A monoclonal antibody reacting with a membrane determinant expressed on activated chicken T lymphocytes

Karel Hála; Konrad Schauenstein; Nikolaus Neu; Guido Krömer; Hugo Wolf; Günther Böck; Georg Wick

doi:10.1002/eji.1830161104

A monoclonal antibody reacting with a membrane determinant expressed on activated chicken T lymphocytes

Karel Hála, Konrad Schauenstein, Nikolaus Neu, Guido Krömer, Hugo Wolf, Günther Böck, Georg Wick

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Abstract

A monoclonal antibody (INN‐CH‐16) was prepared which reacts with a cell surface antigen termed chicken activated T lymphocyte antigen. This antigen is expressed on antigen‐ or mitogen‐activated T lymphocytes and is not present on nonstimulated lymphocytes. It has an apparent molecular mass of 48‐50 kDa under reducing conditions. The value of this antibody for the immunohistochemical characterization of infiltrating cells in the thyroid glands from Obese strain chickens with spontaneous thyroiditis is demonstrated.

Original language	English
Pages (from-to)	1331-1336
Number of pages	6
Journal	European Journal of Immunology
Volume	16
Issue number	11
DOIs	https://doi.org/10.1002/eji.1830161104
Publication status	Published - 1 Jan 1986
Externally published	Yes

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abstract = "A monoclonal antibody (INN‐CH‐16) was prepared which reacts with a cell surface antigen termed chicken activated T lymphocyte antigen. This antigen is expressed on antigen‐ or mitogen‐activated T lymphocytes and is not present on nonstimulated lymphocytes. It has an apparent molecular mass of 48‐50 kDa under reducing conditions. The value of this antibody for the immunohistochemical characterization of infiltrating cells in the thyroid glands from Obese strain chickens with spontaneous thyroiditis is demonstrated.",

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AU - Hála, Karel

AU - Schauenstein, Konrad

AU - Neu, Nikolaus

AU - Krömer, Guido

AU - Wolf, Hugo

AU - Böck, Günther

AU - Wick, Georg

PY - 1986/1/1

Y1 - 1986/1/1

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AB - A monoclonal antibody (INN‐CH‐16) was prepared which reacts with a cell surface antigen termed chicken activated T lymphocyte antigen. This antigen is expressed on antigen‐ or mitogen‐activated T lymphocytes and is not present on nonstimulated lymphocytes. It has an apparent molecular mass of 48‐50 kDa under reducing conditions. The value of this antibody for the immunohistochemical characterization of infiltrating cells in the thyroid glands from Obese strain chickens with spontaneous thyroiditis is demonstrated.

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JO - European Journal of Immunology

JF - European Journal of Immunology

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ER -

A monoclonal antibody reacting with a membrane determinant expressed on activated chicken T lymphocytes

Abstract

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