Anesthesie intraveineuse a objectif de concentration

Translated title of the contribution: Target-controlled intravenous anaesthesia

V. Billard, J. B. Cazalaà, F. Servin, X. Viviand

    Research output: Contribution to journalArticlepeer-review

    29 Citations (Scopus)

    Abstract

    Target-controlled infusion (TCI) is a new delivery system for IV anaesthetic agents with which the anaesthetist targets a plasma drug concentration to achieve a predetermined effect. With this system, the tedious task of calculating the amount of administered drug required to achieve the target concentration is left in charge of a microprocessor which commands the infusion device. TCI has long been used only by a few research teams, but this year a much wider field opens to this delivery system through marketing of Diprifusor(TM), a TCI system specifically designed for administration of propofol in everyday practice. This article describes the rationale for administering IV agents through TCI delivery systems, the pharmacokinetic basis of TCI, the regulations and a broad overview of clinical applications, both recent and yet to come.

    Translated title of the contributionTarget-controlled intravenous anaesthesia
    Original languageFrench
    Pages (from-to)250-273
    Number of pages24
    JournalAnnales Francaises d'Anesthesie et de Reanimation
    Volume16
    Issue number3
    DOIs
    Publication statusPublished - 1 Jan 1997

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