Abstract
Smoking status is essential to know when taking care of a lung cancer patient.Never-smoking patients account for 15% of lung cancer patients, more often women and adenocarcinoma.Environmental tobacco smoke and occupational exposure could be important risk factors.Lung cancer in never-smoker appears to be a distinct entity from lung cancer in smoker, with specific molecular characteristics such as frequent EGFR mutations.New molecular targets are on investigation, such as EML4-ALK translocation.Treatment of lung cancer in never-smoker is getting different from that of smoker with more efficacy of molecular targeted therapies.
Translated title of the contribution | Lung cancer in never smoker: Epidemiology, molecular profiles and treatment |
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Original language | French |
Pages (from-to) | 371-378 |
Number of pages | 8 |
Journal | Presse Medicale |
Volume | 40 |
Issue number | 4 PART1 |
DOIs | |
Publication status | Published - 1 Jan 2011 |