Cannabis et cancer

Stéphane Vignot; Benjamin Besse; Thibault De La Motte Rouge; Christophe Massard; Jean Philippe Spano; Laurent Karila

Cannabis et cancer

Translated title of the contribution: Cannabis and cancer

Stéphane Vignot, Benjamin Besse, Thibault De La Motte Rouge, Christophe Massard, Jean Philippe Spano, Laurent Karila

Research output: Contribution to journal › Review article › peer-review

5 Citations (Scopus)

Abstract

The two varieties of hemp, Cannabis sativa and Cannabis indica, contain about sixty compounds, named cannabinoids. The most abundant molecule, Δ⁹-tetrahydrocannabinol (THC), is involved in the biological effects of cannabis due to its analogy with endogenous, substances (endocannabinoids) thus activating specific receptors: CB1 and CB2. A better knowledge of cannabinoids and their receptors leds to new interrogations, beyond the addictology, in particular in oncology. This review of the literature analyses these questions with special concern on the carcinogenic role of cannabis, the potential antitumor effect of cannabinoids and the place of THC and its derivatives for supportive care in cancerology.

Translated title of the contribution	Cannabis and cancer
Original language	French
Pages (from-to)	163-170
Number of pages	8
Journal	Bulletin du Cancer
Volume	93
Issue number	2
Publication status	Published - 1 Feb 2006
Externally published	Yes

Cite this

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AU - Vignot, Stéphane

AU - Besse, Benjamin

AU - De La Motte Rouge, Thibault

AU - Massard, Christophe

AU - Spano, Jean Philippe

AU - Karila, Laurent

PY - 2006/2/1

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N2 - The two varieties of hemp, Cannabis sativa and Cannabis indica, contain about sixty compounds, named cannabinoids. The most abundant molecule, Δ9-tetrahydrocannabinol (THC), is involved in the biological effects of cannabis due to its analogy with endogenous, substances (endocannabinoids) thus activating specific receptors: CB1 and CB2. A better knowledge of cannabinoids and their receptors leds to new interrogations, beyond the addictology, in particular in oncology. This review of the literature analyses these questions with special concern on the carcinogenic role of cannabis, the potential antitumor effect of cannabinoids and the place of THC and its derivatives for supportive care in cancerology.

AB - The two varieties of hemp, Cannabis sativa and Cannabis indica, contain about sixty compounds, named cannabinoids. The most abundant molecule, Δ9-tetrahydrocannabinol (THC), is involved in the biological effects of cannabis due to its analogy with endogenous, substances (endocannabinoids) thus activating specific receptors: CB1 and CB2. A better knowledge of cannabinoids and their receptors leds to new interrogations, beyond the addictology, in particular in oncology. This review of the literature analyses these questions with special concern on the carcinogenic role of cannabis, the potential antitumor effect of cannabinoids and the place of THC and its derivatives for supportive care in cancerology.

KW - Cancer

KW - Cannabinoide

KW - Cannabis

KW - Tetrahydrocannabinol

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VL - 93

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JO - Bulletin du Cancer

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IS - 2

ER -

Cannabis et cancer

Abstract

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