Caring for patients with cancer in the COVID-19 era

Joris van de Haar; Louisa R. Hoes; Charlotte E. Coles; Kenneth Seamon; Stefan Fröhling; Dirk Jäger; Franco Valenza; Filippo de Braud; Luigi De Petris; Jonas Bergh; Ingemar Ernberg; Benjamin Besse; Fabrice Barlesi; Elena Garralda; Alejandro Piris-Giménez; Michael Baumann; Giovanni Apolone; Jean Charles Soria; Josep Tabernero; Carlos Caldas; Emile E. Voest

doi:10.1038/s41591-020-0874-8

Caring for patients with cancer in the COVID-19 era

Joris van de Haar, Louisa R. Hoes, Charlotte E. Coles, Kenneth Seamon, Stefan Fröhling, Dirk Jäger, Franco Valenza, Filippo de Braud, Luigi De Petris, Jonas Bergh, Ingemar Ernberg, Benjamin Besse, Fabrice Barlesi, Elena Garralda, Alejandro Piris-Giménez, Michael Baumann, Giovanni Apolone, Jean Charles Soria, Josep Tabernero, Carlos CaldasEmile E. Voest

Research output: Contribution to journal › Review article › peer-review

254 Citations (Scopus)

Abstract

The current COVID-19 pandemic challenges oncologists to profoundly re-organize oncological care in order to dramatically reduce hospital visits and admissions and therapy-induced immune-related complications without compromising cancer outcomes. Since COVID-19 is a novel disease, guidance by scientific evidence is often unavailable, and impactful decisions are inevitably made on the basis of expert opinions. Here we report how the seven comprehensive cancer centers of Cancer Core Europe have organized their healthcare systems at an unprecedented scale and pace to make their operations ‘pandemic proof’. We identify and discuss many commonalities, but also important local differences, and pinpoint critical research priorities to enable evidence-based remodeling of cancer care during the COVID-19 pandemic. Also, we discuss how the current situation offers a unique window of opportunity for assessing the effects of de-escalating anticancer regimens, which may fast-forward the development of more-refined and less-toxic treatments. By sharing our joint experiences, we offer a roadmap for proceeding and aim to mobilize the global research community to generate the data that are critically needed to offer the best possible care to patients.

Original language	English
Pages (from-to)	665-671
Number of pages	7
Journal	Nature Medicine
Volume	26
Issue number	5
DOIs	https://doi.org/10.1038/s41591-020-0874-8
Publication status	Published - 1 May 2020

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van de Haar, J., Hoes, L. R., Coles, C. E., Seamon, K., Fröhling, S., Jäger, D., Valenza, F., de Braud, F., De Petris, L., Bergh, J., Ernberg, I., Besse, B., Barlesi, F., Garralda, E., Piris-Giménez, A., Baumann, M., Apolone, G., Soria, J. C., Tabernero, J., ... Voest, E. E. (2020). Caring for patients with cancer in the COVID-19 era. Nature Medicine, 26(5), 665-671. https://doi.org/10.1038/s41591-020-0874-8

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title = "Caring for patients with cancer in the COVID-19 era",

abstract = "The current COVID-19 pandemic challenges oncologists to profoundly re-organize oncological care in order to dramatically reduce hospital visits and admissions and therapy-induced immune-related complications without compromising cancer outcomes. Since COVID-19 is a novel disease, guidance by scientific evidence is often unavailable, and impactful decisions are inevitably made on the basis of expert opinions. Here we report how the seven comprehensive cancer centers of Cancer Core Europe have organized their healthcare systems at an unprecedented scale and pace to make their operations {\textquoteleft}pandemic proof{\textquoteright}. We identify and discuss many commonalities, but also important local differences, and pinpoint critical research priorities to enable evidence-based remodeling of cancer care during the COVID-19 pandemic. Also, we discuss how the current situation offers a unique window of opportunity for assessing the effects of de-escalating anticancer regimens, which may fast-forward the development of more-refined and less-toxic treatments. By sharing our joint experiences, we offer a roadmap for proceeding and aim to mobilize the global research community to generate the data that are critically needed to offer the best possible care to patients.",

author = "{van de Haar}, Joris and Hoes, {Louisa R.} and Coles, {Charlotte E.} and Kenneth Seamon and Stefan Fr{\"o}hling and Dirk J{\"a}ger and Franco Valenza and {de Braud}, Filippo and {De Petris}, Luigi and Jonas Bergh and Ingemar Ernberg and Benjamin Besse and Fabrice Barlesi and Elena Garralda and Alejandro Piris-Gim{\'e}nez and Michael Baumann and Giovanni Apolone and Soria, {Jean Charles} and Josep Tabernero and Carlos Caldas and Voest, {Emile E.}",

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year = "2020",

month = may,

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doi = "10.1038/s41591-020-0874-8",

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van de Haar, J, Hoes, LR, Coles, CE, Seamon, K, Fröhling, S, Jäger, D, Valenza, F, de Braud, F, De Petris, L, Bergh, J, Ernberg, I, Besse, B, Barlesi, F, Garralda, E, Piris-Giménez, A, Baumann, M, Apolone, G, Soria, JC, Tabernero, J, Caldas, C & Voest, EE 2020, 'Caring for patients with cancer in the COVID-19 era', Nature Medicine, vol. 26, no. 5, pp. 665-671. https://doi.org/10.1038/s41591-020-0874-8

TY - JOUR

T1 - Caring for patients with cancer in the COVID-19 era

AU - van de Haar, Joris

AU - Hoes, Louisa R.

AU - Coles, Charlotte E.

AU - Seamon, Kenneth

AU - Fröhling, Stefan

AU - Jäger, Dirk

AU - Valenza, Franco

AU - de Braud, Filippo

AU - De Petris, Luigi

AU - Bergh, Jonas

AU - Ernberg, Ingemar

AU - Besse, Benjamin

AU - Barlesi, Fabrice

AU - Garralda, Elena

AU - Piris-Giménez, Alejandro

AU - Baumann, Michael

AU - Apolone, Giovanni

AU - Soria, Jean Charles

AU - Tabernero, Josep

AU - Caldas, Carlos

AU - Voest, Emile E.

PY - 2020/5/1

Y1 - 2020/5/1

N2 - The current COVID-19 pandemic challenges oncologists to profoundly re-organize oncological care in order to dramatically reduce hospital visits and admissions and therapy-induced immune-related complications without compromising cancer outcomes. Since COVID-19 is a novel disease, guidance by scientific evidence is often unavailable, and impactful decisions are inevitably made on the basis of expert opinions. Here we report how the seven comprehensive cancer centers of Cancer Core Europe have organized their healthcare systems at an unprecedented scale and pace to make their operations ‘pandemic proof’. We identify and discuss many commonalities, but also important local differences, and pinpoint critical research priorities to enable evidence-based remodeling of cancer care during the COVID-19 pandemic. Also, we discuss how the current situation offers a unique window of opportunity for assessing the effects of de-escalating anticancer regimens, which may fast-forward the development of more-refined and less-toxic treatments. By sharing our joint experiences, we offer a roadmap for proceeding and aim to mobilize the global research community to generate the data that are critically needed to offer the best possible care to patients.

AB - The current COVID-19 pandemic challenges oncologists to profoundly re-organize oncological care in order to dramatically reduce hospital visits and admissions and therapy-induced immune-related complications without compromising cancer outcomes. Since COVID-19 is a novel disease, guidance by scientific evidence is often unavailable, and impactful decisions are inevitably made on the basis of expert opinions. Here we report how the seven comprehensive cancer centers of Cancer Core Europe have organized their healthcare systems at an unprecedented scale and pace to make their operations ‘pandemic proof’. We identify and discuss many commonalities, but also important local differences, and pinpoint critical research priorities to enable evidence-based remodeling of cancer care during the COVID-19 pandemic. Also, we discuss how the current situation offers a unique window of opportunity for assessing the effects of de-escalating anticancer regimens, which may fast-forward the development of more-refined and less-toxic treatments. By sharing our joint experiences, we offer a roadmap for proceeding and aim to mobilize the global research community to generate the data that are critically needed to offer the best possible care to patients.

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DO - 10.1038/s41591-020-0874-8

M3 - Review article

C2 - 32405058

AN - SCOPUS:85083781955

SN - 1078-8956

VL - 26

SP - 665

EP - 671

JO - Nature Medicine

JF - Nature Medicine

IS - 5

ER -

Caring for patients with cancer in the COVID-19 era

Abstract

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