Chemotherapy in the management of periosteal osteosarcoma: A narrative review

Tarek Assi, Joseph Kattan, Hussein Nassereddine, Elie Rassy, Sylvain Briand, Charles Court, Benjamin Verret, Axel Le Cesne, Olivier Mir

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    11 Citations (Scopus)

    Abstract

    Periosteal osteosarcoma (PO), an intermediate-grade chondroblastic osteosarcoma (OST) arising from the surface of the bones, is a rare histological subtype among primary bone sarcomas, most commonly diagnosed in young patients. It is characterized by distinct specific radiological and pathological features. The current management strategy is based on several case reports and series, without any solid international recommendations. Most sarcoma experts agree on the crucial role of an optimal complete surgical approach. However, with the paucity of available reports, the role of systemic treatment and its timing remains debatable. With this paper, we will review the available data on the actual impact of chemotherapy in PO patients with emphasis on the radiological, pathological, and therapeutic characteristics of this rare entity.

    Original languageEnglish
    Article number100389
    JournalJournal of Bone Oncology
    Volume30
    DOIs
    Publication statusPublished - 1 Oct 2021

    Keywords

    • Bone tumors
    • Chemotherapy
    • Osteosarcoma
    • Periosteal osteosarcoma
    • Sarcoma

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