DCE-US: Evaluation of angiogenesis

Nathalie Lassau

    Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

    Abstract

    In the era of personalised medicine, imaging indicators of tumour response are needed to guide patient management. Recent technical advances in DCE-US enable measurements of perfusion to quantify the microvascularisation in tumours. Reduction of vascularisation is detectable in responders after 2 weeks treatment and is correlated with progression-free and overall survival in renal and hepatocellular carcinomas. A recent multicentric study of DCE-US (539 patients) demonstrated that the area under the curve is a robust predictor of response at 1 month in several types of body tumours.

    Original languageEnglish
    Title of host publicationFunctional Imaging in Oncology
    Subtitle of host publicationBiophysical Basis and Technical Approaches - Volume 1
    PublisherSpringer Berlin Heidelberg
    Pages377-388
    Number of pages12
    ISBN (Electronic)9783642404122
    ISBN (Print)9783642404115
    DOIs
    Publication statusPublished - 1 Jan 2014

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