Abstract
In the era of personalised medicine, imaging indicators of tumour response are needed to guide patient management. Recent technical advances in DCE-US enable measurements of perfusion to quantify the microvascularisation in tumours. Reduction of vascularisation is detectable in responders after 2 weeks treatment and is correlated with progression-free and overall survival in renal and hepatocellular carcinomas. A recent multicentric study of DCE-US (539 patients) demonstrated that the area under the curve is a robust predictor of response at 1 month in several types of body tumours.
Original language | English |
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Title of host publication | Functional Imaging in Oncology |
Subtitle of host publication | Biophysical Basis and Technical Approaches - Volume 1 |
Publisher | Springer Berlin Heidelberg |
Pages | 377-388 |
Number of pages | 12 |
ISBN (Electronic) | 9783642404122 |
ISBN (Print) | 9783642404115 |
DOIs | |
Publication status | Published - 1 Jan 2014 |