Drug-induced Nail Changes

Robert Baran, Bruno Fouilloux, Caroline Robert

    Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

    3 Citations (Scopus)

    Abstract

    Many side-effects of drugs on the nails are now well known. Some are classic while others have been recently described. Since the last edition of this book, antineoplastic drugs have been recognized as affecting the nails. Many nail signs have been described with these treatments, including onycholysis, hematomas, perionyxis and pyogenic granuloma. The severity of the discomfort can sometime necessitate cessation of therapy. Besides these new drugs, side-effects observed during treatment with retinoids, cyclines, antiretroviral drugs, cardiovascular drugs and antimalarial drugs are well known. Some side-effects described with new drugs are more confidential [AQ: not sure what you mean by 'confidential'] such as those seen with anti-TFN, cyclosporine, selenium, antifungals, reverse transcriptase inhibitor therapy, salsalate and interferon. Toxic drugs such as arsenic, silver, mercury, thallium and polychlorinated biphenyls are also responsible for nail changes.

    Original languageEnglish
    Title of host publicationBaran & Dawber's Diseases of the Nails and their Management: Fourth Edition
    PublisherBlackwell Publishing Ltd
    Pages413-442
    Number of pages30
    ISBN (Print)9780470657355
    DOIs
    Publication statusPublished - 23 May 2012

    Keywords

    • Antifungals
    • Antimalarial agents
    • Antiretroviral drugs
    • Cardiovascular drugs
    • Chemotherapeutic agents
    • Cyclines
    • Drugs
    • Nail changes
    • Photoonycholysis
    • Retinoids
    • Toxics

    Cite this