Endosome positioning during cytokinesis

Guillaume Montagnac, Philippe Chavrier

Research output: Contribution to journalReview articlepeer-review

12 Citations (Scopus)

Abstract

In mammalian cells, completion of cytokinesis relies on targeted delivery of recycling membranes to the midbody. At this step of mitosis, recycling endosomes are organized as clusters located at the mitotic spindle poles as well as at both sides of the midbody. However, the mechanism that controls endosome positioning during cytokinesis is not known. Here, we discuss the possible mechanisms that drive the formation of endosomal clusters and the importance of this process for the targeted delivery of recycling membranes to the midbody.

Original languageEnglish
Pages (from-to)442-443
Number of pages2
JournalBiochemical Society Transactions
Volume36
Issue number3
DOIs
Publication statusPublished - 1 Jun 2008
Externally publishedYes

Keywords

  • Cytokinesis
  • Endosome
  • Membrane recycling
  • Microtubule

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