Familial primary mediastinal nonseminomatous germ-cell tumors

Adina Marti; Stéphane Culine; Patrice Carde; Bertrand Paugam; Karim Fizazi

doi:10.1016/S1078-1439(03)00178-9

Familial primary mediastinal nonseminomatous germ-cell tumors

Adina Marti, Stéphane Culine, Patrice Carde, Bertrand Paugam, Karim Fizazi

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

In this article, we describe the case of 4 brothers, 2 of which had primary mediastinal nonseminomatous germ cell tumors (PMNSGCT), while the other 2 had benign mediastinal disease. We discuss the relationship between these diseases of the mediastinum and the thymic microenvironment. Additionally, we suggest that a genetic predisposition for germ-cell tumors (GCT) may be involved since the parents were relatives.

Original language	English
Pages (from-to)	421-424
Number of pages	4
Journal	Urologic Oncology: Seminars and Original Investigations
Volume	22
Issue number	5
DOIs	https://doi.org/10.1016/S1078-1439(03)00178-9
Publication status	Published - 1 Jan 2004

Keywords

Chemotherapy
Genetics
Primary mediastinal nonseminomatous germ cell tumor
Thymus microenvironment

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10.1016/S1078-1439(03)00178-9

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abstract = "In this article, we describe the case of 4 brothers, 2 of which had primary mediastinal nonseminomatous germ cell tumors (PMNSGCT), while the other 2 had benign mediastinal disease. We discuss the relationship between these diseases of the mediastinum and the thymic microenvironment. Additionally, we suggest that a genetic predisposition for germ-cell tumors (GCT) may be involved since the parents were relatives.",

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AU - Fizazi, Karim

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KW - Chemotherapy

KW - Genetics

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KW - Thymus microenvironment

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Familial primary mediastinal nonseminomatous germ-cell tumors

Abstract

Keywords

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