Histamine antagonists promote cancer immunosurveillance

Peng Liu; Guido Kroemer; Oliver Kepp

doi:10.1080/2162402X.2023.2242211

Histamine antagonists promote cancer immunosurveillance

Peng Liu, Guido Kroemer, Oliver Kepp

Research output: Contribution to journal › Comment/debate

2 Citations (Scopus)

Abstract

Recently, a cellular mini-immune system comprising infinitely expandable dendritic cells and T cells led to the discovery that histamine receptor H1 antagonists act on T cells to stimulate their proliferation and polarization toward a Th1/Tc1 phenotype and to increase their anticancer activity in the context of immunochemotherapy.

Original language	English
Article number	2242211
Journal	OncoImmunology
Volume	12
Issue number	1
DOIs	https://doi.org/10.1080/2162402X.2023.2242211
Publication status	Published - 1 Jan 2023

Keywords

cancer
cell death
immunotherapy

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10.1080/2162402X.2023.2242211

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title = "Histamine antagonists promote cancer immunosurveillance",

abstract = "Recently, a cellular mini-immune system comprising infinitely expandable dendritic cells and T cells led to the discovery that histamine receptor H1 antagonists act on T cells to stimulate their proliferation and polarization toward a Th1/Tc1 phenotype and to increase their anticancer activity in the context of immunochemotherapy.",

keywords = "cancer, cell death, immunotherapy",

author = "Peng Liu and Guido Kroemer and Oliver Kepp",

note = "Publisher Copyright: {\textcopyright} 2023 The Author(s). Published with license by Taylor & Francis Group, LLC.",

year = "2023",

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doi = "10.1080/2162402X.2023.2242211",

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T1 - Histamine antagonists promote cancer immunosurveillance

AU - Liu, Peng

AU - Kroemer, Guido

AU - Kepp, Oliver

PY - 2023/1/1

Y1 - 2023/1/1

N2 - Recently, a cellular mini-immune system comprising infinitely expandable dendritic cells and T cells led to the discovery that histamine receptor H1 antagonists act on T cells to stimulate their proliferation and polarization toward a Th1/Tc1 phenotype and to increase their anticancer activity in the context of immunochemotherapy.

AB - Recently, a cellular mini-immune system comprising infinitely expandable dendritic cells and T cells led to the discovery that histamine receptor H1 antagonists act on T cells to stimulate their proliferation and polarization toward a Th1/Tc1 phenotype and to increase their anticancer activity in the context of immunochemotherapy.

KW - cancer

KW - cell death

KW - immunotherapy

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U2 - 10.1080/2162402X.2023.2242211

DO - 10.1080/2162402X.2023.2242211

M3 - Comment/debate

C2 - 37554311

AN - SCOPUS:85167340594

SN - 2162-4011

VL - 12

JO - OncoImmunology

JF - OncoImmunology

IS - 1

M1 - 2242211

ER -

Histamine antagonists promote cancer immunosurveillance

Abstract

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