Hope in the Long Road Toward the Development of a Therapeutic Human Papillomavirus Vaccine

Soumaya Karaki; Helene Pere; Cecile Badoual; Eric Tartour

doi:10.1158/1078-0432.CCR-16-0216

Hope in the Long Road Toward the Development of a Therapeutic Human Papillomavirus Vaccine

Soumaya Karaki, Helene Pere, Cecile Badoual, Eric Tartour

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

A pool of long synthetic peptides derived from HPV16 proteins induce objective partial or complete histologic regression of lesions in more than 50% of patients with high-grade vulvar (VuVIN3) and vaginal intraepithelial neoplasia (VaIN3). The intensity of T-cell response induced by the vaccine was correlated with clinical response.

Original language	English
Pages (from-to)	2317-2319
Number of pages	3
Journal	Clinical Cancer Research
Volume	22
Issue number	10
DOIs	https://doi.org/10.1158/1078-0432.CCR-16-0216
Publication status	Published - 15 May 2016
Externally published	Yes

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10.1158/1078-0432.CCR-16-0216

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abstract = "A pool of long synthetic peptides derived from HPV16 proteins induce objective partial or complete histologic regression of lesions in more than 50% of patients with high-grade vulvar (VuVIN3) and vaginal intraepithelial neoplasia (VaIN3). The intensity of T-cell response induced by the vaccine was correlated with clinical response.",

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AU - Pere, Helene

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AU - Tartour, Eric

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AB - A pool of long synthetic peptides derived from HPV16 proteins induce objective partial or complete histologic regression of lesions in more than 50% of patients with high-grade vulvar (VuVIN3) and vaginal intraepithelial neoplasia (VaIN3). The intensity of T-cell response induced by the vaccine was correlated with clinical response.

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Hope in the Long Road Toward the Development of a Therapeutic Human Papillomavirus Vaccine

Abstract

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