Hyperthermic intraperitoneal chemotherapy in the treatment of peritoneal carcinomatosis of digestive and peritoneal origin: Rationale

G. Liberale, M. Pocard, D. Manganas, M. Ducreux, P. Lasser, D. Elias

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    Abstract

    Up to a few years ago peritoneal carcinomatosis was considered as an "incurable" disease. The aim of this paper is to review the surgical approach with curative intent to carcinomatosis: it consists of complete resection of macroscopic disease (R1), associated with hyperthermic intraperitoneal chemotherapy (HIPEC) to treat residual microscopic disease, and to evaluate its indications. Overall 5-year survival of patients with peritoneal carcinomatosis treated by HIPEC is similar to that of patients with hepatic metastases treated with curative intent. Those patients should no longer be considered as patients with a terminal disease but as patients with a potentially treatable localized disease.

    Original languageEnglish
    Pages (from-to)291-296
    Number of pages6
    JournalActa Chirurgica Belgica
    Volume106
    Issue number3
    DOIs
    Publication statusPublished - 1 Jan 2006

    Keywords

    • Carcinomatosis
    • Digestive cancers
    • Hyperthermic
    • Intraperitoneal chemotherapy (HIPEC)
    • Peritoneal
    • Peritonectomy
    • Primitive peritoneal tumours

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