Abstract
Breast cancer is the most common cancer diagnosed and the first leading cause of cancer death among women in France. A population of women at high risk of breast cancer (more than 3% risk at 5 years and 20–25% lifetime) can nowadays be identified and benefit from an appropriate personalized prevention and monitoring program. The French national health authority (HAS, Haute Autorité de Santé) considers personal germline mutation of BRCA1/2, TP53, PTEN, CDH1 or STK11/LKB1 genes, but also recently personal breast cancer history, personal history of atypical breast lesion, history of high-dose chest irradiation and striking family breast/ovarian cancer history but without identified mutation, as criteria of high breast cancer risk and provides screening recommendations for these women.
Translated title of the contribution | Identification and management of high risks of breast cancer. State of the art in 2014 |
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Original language | French |
Pages (from-to) | 413-418 |
Number of pages | 6 |
Journal | Oncologie |
Volume | 16 |
Issue number | 9-10 |
DOIs | |
Publication status | Published - 31 Oct 2014 |