Intracerebral small round cell tumor: An unusual case with EWS-WT1 translocation

Karim Bouchireb; Nathalie Auger; Ranjeev Bhangoo; Federico Di Rocco; Nicole Brousse; Olivier Delattre; Pascale Varlet; Jacques Grill

doi:10.1002/pbc.21648

Intracerebral small round cell tumor: An unusual case with EWS-WT1 translocation

Karim Bouchireb, Nathalie Auger, Ranjeev Bhangoo, Federico Di Rocco, Nicole Brousse, Olivier Delattre, Pascale Varlet, Jacques Grill

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Abstract

Desmoplastic small round cell tumor (DSRCT) is a rare tumor, seen both in children and young adults with a marked predilection for the peritoneal cavity. Histology showed a small round cell tumor with a fibromyxoïd stroma and immunohistochemistry indicated neural and mesenchymal differentiation, and diagnosis was made by molecular detection of the EWS-WT1 fusion gene product. DSRCT should be considered in the differential diagnosis of intracranial small round cell tumors.

Original language	English
Pages (from-to)	545-548
Number of pages	4
Journal	Pediatric Blood and Cancer
Volume	51
Issue number	4
DOIs	https://doi.org/10.1002/pbc.21648
Publication status	Published - 1 Oct 2008

Keywords

Brain
Desmoplastic small round cell tumor
EWS-WT1 translocation

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10.1002/pbc.21648

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abstract = "Desmoplastic small round cell tumor (DSRCT) is a rare tumor, seen both in children and young adults with a marked predilection for the peritoneal cavity. Histology showed a small round cell tumor with a fibromyxo{\"i}d stroma and immunohistochemistry indicated neural and mesenchymal differentiation, and diagnosis was made by molecular detection of the EWS-WT1 fusion gene product. DSRCT should be considered in the differential diagnosis of intracranial small round cell tumors.",

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AU - Bouchireb, Karim

AU - Auger, Nathalie

AU - Bhangoo, Ranjeev

AU - Di Rocco, Federico

AU - Brousse, Nicole

AU - Delattre, Olivier

AU - Varlet, Pascale

AU - Grill, Jacques

PY - 2008/10/1

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N2 - Desmoplastic small round cell tumor (DSRCT) is a rare tumor, seen both in children and young adults with a marked predilection for the peritoneal cavity. Histology showed a small round cell tumor with a fibromyxoïd stroma and immunohistochemistry indicated neural and mesenchymal differentiation, and diagnosis was made by molecular detection of the EWS-WT1 fusion gene product. DSRCT should be considered in the differential diagnosis of intracranial small round cell tumors.

AB - Desmoplastic small round cell tumor (DSRCT) is a rare tumor, seen both in children and young adults with a marked predilection for the peritoneal cavity. Histology showed a small round cell tumor with a fibromyxoïd stroma and immunohistochemistry indicated neural and mesenchymal differentiation, and diagnosis was made by molecular detection of the EWS-WT1 fusion gene product. DSRCT should be considered in the differential diagnosis of intracranial small round cell tumors.

KW - Brain

KW - Desmoplastic small round cell tumor

KW - EWS-WT1 translocation

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IS - 4

ER -

Intracerebral small round cell tumor: An unusual case with EWS-WT1 translocation

Abstract

Keywords

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