La perfusion pelvienne sous circulation extracorporelle dans les tumeurs pelviennes localement évoluées

Translated title of the contribution: Pelvic perfusion for localy advanced tumors

Sylvie Bonvalot, Jane Muret, Thierry Debaere

    Research output: Contribution to journalReview articlepeer-review

    7 Citations (Scopus)

    Abstract

    Isolated pelvic perfusion (IPP) is a method of intra-arterial local-regional treatment using a simplified balloon occlusion technique. It achieved high-dose drug concentration in pelvis with the minimal adverse effects. Recently, this approach was improved with the use of a pressure-suit placed above the level of aortic and caval stop-flow. A better ratio between pelvic and systemic compartments was achieved. This stop-flow technique with low dose TNF-α and melphalan has shown promise in palliation of resectability of advanced cancer in patients not amenable to treatment with conventional chemo radiation in a comparable proportion to those obtained with isolated limb perfusions. A randomized study will start soon.

    Translated title of the contributionPelvic perfusion for localy advanced tumors
    Original languageFrench
    Pages (from-to)103-109
    Number of pages7
    JournalBulletin du Cancer
    Volume96
    Issue number1
    DOIs
    Publication statusPublished - 1 Jan 2009

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