Abstract
Isolated pelvic perfusion (IPP) is a method of intra-arterial local-regional treatment using a simplified balloon occlusion technique. It achieved high-dose drug concentration in pelvis with the minimal adverse effects. Recently, this approach was improved with the use of a pressure-suit placed above the level of aortic and caval stop-flow. A better ratio between pelvic and systemic compartments was achieved. This stop-flow technique with low dose TNF-α and melphalan has shown promise in palliation of resectability of advanced cancer in patients not amenable to treatment with conventional chemo radiation in a comparable proportion to those obtained with isolated limb perfusions. A randomized study will start soon.
Translated title of the contribution | Pelvic perfusion for localy advanced tumors |
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Original language | French |
Pages (from-to) | 103-109 |
Number of pages | 7 |
Journal | Bulletin du Cancer |
Volume | 96 |
Issue number | 1 |
DOIs | |
Publication status | Published - 1 Jan 2009 |