Late Recurrent Testicular Seminoma: Histological Evidence Is Required

Cedric Lebacle, Marco Gizzi, Jean Marie Michot, Olivier Lambotte, Felix Ackermann, Thierry Lazure, Christophe Massard

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Introduction: Over the past 3 decades, the appropriate management of metastatic germ cell tumours (GCT) has been defined by several phase III trials. Many follow-up recommendations have been published based on expert consensus. However, common clinical scenarios can still be vexing for clinicians who are less experienced at managing patients with testicular cancer. Case Report: We highlight the arduous diagnostic work-up of a suspected late relapsing metastatic GCT in a patient suffering from fatigue, weight loss and prominent retroperitoneal lymph nodes, 4 years after first-line chemotherapy for metastatic seminoma. The various explorations finally led to the diagnosis of Whipple's disease. Conclusion: This unusual clinical case strongly highlights the need to perform an exhaustive evaluation, with a biopsy, if a late recurrent GCT is suspected to avoid pointless and potentially harmful treatment.

    Original languageEnglish
    Pages (from-to)286-288
    Number of pages3
    JournalOncology Research and Treatment
    Volume38
    Issue number6
    DOIs
    Publication statusPublished - 1 Jun 2015

    Keywords

    • Lymph node status
    • Recurrence
    • Seminoma
    • Testicular cancer

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