Lysosome-targeting agents in cancer therapy

Guido Kroemer, Lorenzo Galluzzi

    Research output: Contribution to journalArticlepeer-review

    13 Citations (Scopus)

    Abstract

    Despite considerable efforts from multiple laboratories worldwide, highly specific inhibitors of autophagy for clinical use are not yet available. Lysosomal inhibitors are being employed instead, in spite of multiple limitations that are summarized herein.

    Original languageEnglish
    Pages (from-to)112168-112169
    Number of pages2
    JournalOncotarget
    Volume8
    Issue number68
    DOIs
    Publication statusPublished - 1 Jan 2017

    Keywords

    • Anticancer immunosurveillance
    • Autophagy
    • Chemotherapy
    • Chloroquine
    • Hydroxychloroquine

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