Macrophages in radiation injury: a new therapeutic target

Lydia Meziani; Eric Deutsch; Michele Mondini

doi:10.1080/2162402X.2018.1494488

Macrophages in radiation injury: a new therapeutic target

Lydia Meziani, Eric Deutsch, Michele Mondini

Research output: Contribution to journal › Article › peer-review

51 Citations (Scopus)

Abstract

Radiotherapy can induce toxicity in healthy tissues such as radiation-induced fibrosis (RIF), and macrophages are proposed as new profibrogenic cells. In this Point-of-View, we summarize the role of the immune response in ionizing radiation injury, and we focus on macrophages as a new therapeutic target in RIF.

Original language	English
Article number	e1494488
Journal	OncoImmunology
Volume	7
Issue number	10
DOIs	https://doi.org/10.1080/2162402X.2018.1494488
Publication status	Published - 3 Oct 2018

Keywords

Radiation injury
immune system
lung fibrosis
macrophages
radiation toxicity

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10.1080/2162402X.2018.1494488

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title = "Macrophages in radiation injury: a new therapeutic target",

abstract = "Radiotherapy can induce toxicity in healthy tissues such as radiation-induced fibrosis (RIF), and macrophages are proposed as new profibrogenic cells. In this Point-of-View, we summarize the role of the immune response in ionizing radiation injury, and we focus on macrophages as a new therapeutic target in RIF.",

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AU - Deutsch, Eric

AU - Mondini, Michele

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AB - Radiotherapy can induce toxicity in healthy tissues such as radiation-induced fibrosis (RIF), and macrophages are proposed as new profibrogenic cells. In this Point-of-View, we summarize the role of the immune response in ionizing radiation injury, and we focus on macrophages as a new therapeutic target in RIF.

KW - Radiation injury

KW - immune system

KW - lung fibrosis

KW - macrophages

KW - radiation toxicity

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Macrophages in radiation injury: a new therapeutic target

Abstract

Keywords

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