Mesure de la mortalité à 120jours après biopsie de la prostate

Objective: Concerning death-rates were reported following prostate biopsy but the lack of contexts in which event occurred makes it difficult to take any position. Therefore, we aimed to determine the 120-day post-biopsy mortality rate. Material and methods: Between 2000and 2011, 8804men underwent prostate biopsy in the hospice civils de Lyon. We studied retrospectively, the mortality rate after each of the 11,816procedures. Biopsies imputability was assessed by examining all medical records. Dates of death were extracted from our local patient management database, which is updated trimestrially with death notifications from the French National Institute for Statistics and Economic Studies. Results: In our study 42deaths occurred within 120. days after 11,816prostate biopsies (0.36%). Of the 42records: 9were lost to follow-up, 3had no identifiable cause of death, 28had an intercurrent event ruling out prostate biopsy as a cause of death. Only 2deaths could be linked to biopsy. Conclusions: We reported at most 2deaths possibly related to prostate biopsy over 11,816procedures (0.02%). We confirmed the fact that prostate biopsies can be lethal but this rare outcome should not be considered as an argument against prostate screening given the circumstances in which it occurs. Level of evidence: 5.