Necroptosis Turns TNF Lethal

Lorenzo Galluzzi, Guido Kroemer

    Research output: Contribution to journalShort surveypeer-review

    12 Citations (Scopus)

    Abstract

    In this issue of Immunity, Duprez et al. (2011) demonstrate that necroptosis, a form of regulated necrosis that is mediated by the kinases RIPK1 and RIPK3, underlies the lethal effects of tumor necrosis factor in vivo.

    Original languageEnglish
    Pages (from-to)849-851
    Number of pages3
    JournalImmunity
    Volume35
    Issue number6
    DOIs
    Publication statusPublished - 23 Dec 2011

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