TY - JOUR
T1 - Nutritional risk factors in planned oncologic surgery
T2 - What clinical and biological parameters should be routinely used?
AU - Antoun, Sami
AU - Rey, Annie
AU - Béal, Jacqueline
AU - Montange, Fabienne
AU - Pressoir, Martine
AU - Vasson, Marie Paule
AU - Dupoiron, Denis
AU - Gourdiat-Borye, Anne
AU - Guillaume, Alain
AU - Maget, Brigitte
AU - Nitenberg, Gérard
AU - Raynard, Bruno
AU - Bachmann, Patrick
PY - 2009/8/1
Y1 - 2009/8/1
N2 - Background: Screening for malnutrition is recommended in hospitalized and planned surgical patients. The aim of this study was to analyze the feasibility and routine prognostic value of using the principal recommended nutritional screening and evaluation tools for cancer patients undergoing major surgery. Methods: This study is a prospective, 3-month, multicenter observational trial recording weight loss, body mass index, albumin, transthyretin, and PG-SGA. The morbidity rate was assessed on the basis of major complications (MC), whether of an infectious (MIC) or noninfectious (MNIC) nature. Results: Two hundred seventy-five patients were recruited at nine centers. The following percentages were recorded with respect to morbidity: 28.4% MC, 12.7% MIC, and 22.2% MNIC. Univariate analysis revealed a statistical association only between weight loss greater than 10% and MIC and hospital stay. A weight loss of 15% is required to demonstrate an association with either MC, MIC, or MNIC. Body mass index (BMI) was associated only with MNIC, PG-SGA with MC, and albumin <30 g/l was strongly associated with all types of morbidity (MC, MIC, MNIC). Multivariate analysis indicated that only albumin <30 g/l and an operating time of more than 4 h are significantly associated with morbidity. Conclusions: In this study, the best nutritional factor for detecting the risk of MC is albumin levels below 30 g/l. A weight loss greater than 15% is required to obtain a statistically significant correlation with the existence of MC.
AB - Background: Screening for malnutrition is recommended in hospitalized and planned surgical patients. The aim of this study was to analyze the feasibility and routine prognostic value of using the principal recommended nutritional screening and evaluation tools for cancer patients undergoing major surgery. Methods: This study is a prospective, 3-month, multicenter observational trial recording weight loss, body mass index, albumin, transthyretin, and PG-SGA. The morbidity rate was assessed on the basis of major complications (MC), whether of an infectious (MIC) or noninfectious (MNIC) nature. Results: Two hundred seventy-five patients were recruited at nine centers. The following percentages were recorded with respect to morbidity: 28.4% MC, 12.7% MIC, and 22.2% MNIC. Univariate analysis revealed a statistical association only between weight loss greater than 10% and MIC and hospital stay. A weight loss of 15% is required to demonstrate an association with either MC, MIC, or MNIC. Body mass index (BMI) was associated only with MNIC, PG-SGA with MC, and albumin <30 g/l was strongly associated with all types of morbidity (MC, MIC, MNIC). Multivariate analysis indicated that only albumin <30 g/l and an operating time of more than 4 h are significantly associated with morbidity. Conclusions: In this study, the best nutritional factor for detecting the risk of MC is albumin levels below 30 g/l. A weight loss greater than 15% is required to obtain a statistically significant correlation with the existence of MC.
UR - http://www.scopus.com/inward/record.url?scp=68149139645&partnerID=8YFLogxK
U2 - 10.1007/s00268-009-0033-3
DO - 10.1007/s00268-009-0033-3
M3 - Article
C2 - 19387725
AN - SCOPUS:68149139645
SN - 0364-2313
VL - 33
SP - 1633
EP - 1640
JO - World Journal of Surgery
JF - World Journal of Surgery
IS - 8
ER -