Part II drafted from the short text of the French guidelines entitled “Initial management of patients with epithelial ovarian cancer” developed by FRANCOGYN, CNGOF, SFOG, GINECO-ARCAGY and endorsed by INCa. (Systemic and intraperitoneal treatment, elderly, fertility preservation, follow-up)

V. Lavoué, C. Huchon, C. Akladios, P. Alfonsi, N. Bakrin, M. Ballester, S. Bendifallah, P. A. Bolze, F. Bonnet, C. Bourgin, N. Chabbert-Buffet, P. Collinet, B. Courbiere, T. De la Motte Rouge, M. Devouassoux-Shisheboran, C. Falandry, G. Ferron, L. Fournier, L. Gladieff, F. GolfierS. Gouy, F. Guyon, E. Lambaudie, A. Leary, F. Lécuru, M. A. Lefrère-Belda, E. Leblanc, A. Lemoine, F. Narducci, L. Ouldamer, P. Pautier, F. Planchamp, N. Pouget, I. Ray-Coquard, C. Rousset-Jablonski, C. Sénéchal-Davin, C. Touboul, I. Thomassin-Naggara, C. Uzan, B. You, E. Daraï

    Research output: Contribution to journalArticlepeer-review

    5 Citations (Scopus)

    Abstract

    Adjuvant chemotherapy with carboplatin and paclitaxel is recommended for all high-grade ovarian or Fallopian tube cancers, stage FIGO I-IIA (grade A). After a complete first surgery, it is recommended to deliver 6 cycles of intravenous (grade A) or to propose intraperitoneal (grade B) chemotherapy, to be discussed with patient, according to the benefit/risk ratio. After a complete interval surgery for a FIGO III stage, the hyperthermic intra peritoneal chemotherapy (HIPEC) can be proposed in the same conditions of the OV-HIPEC trial (grade B). In case of tumor residue after surgery or FIGO stage IV, chemotherapy associated with bevacizumab is recommended (grade A). For BRCA mutated patient, Olaparib is recommended (grade B).

    Translated title of the contributionPartie 2 rédigée à partir de la synthèse de la recommandation nationale de bonnes pratiques cliniques intitulée « Conduites à tenir initiales devant des patientes atteintes d'un cancer épithélial de l'ovaire » élaborée par FRANCOGYN, CNGOF, SFOG, GINECO-ARCAGY et labélisée par l'INCa. (Traitement systémique et intrapéritonéal, personnes âgées, préservation de la fertilité et suivi)
    Original languageEnglish
    Pages (from-to)111-119
    Number of pages9
    JournalGynecologie Obstetrique Fertilite et Senologie
    Volume47
    Issue number2
    DOIs
    Publication statusPublished - 1 Feb 2019

    Keywords

    • Chemotherapy
    • Fallopian tube cancer
    • Guidelines
    • Ovarian cancer
    • Peritoneal cancer
    • Surgery

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