Prédisposition génétique aux cancers du sein et de l'ovaire: Diagnostic moléculaire et conséquences

S. Delaloge; L. Albiges; B. Bressac—de Paillerets; A. Chompret

doi:10.1007/s10269-006-0361-y

Prédisposition génétique aux cancers du sein et de l'ovaire: Diagnostic moléculaire et conséquences

Translated title of the contribution: Genetic predisposition to breast and ovarian cancer: Molecular diagnosis and consequences

S. Delaloge, L. Albiges, B. Bressac—de Paillerets, A. Chompret

Research output: Contribution to journal › Article › peer-review

Abstract

The molecular diagnosis of a genetic predisposition to breast cancer is now routinely available. BRCA1 and BRCA2 deleterious germline mutations confer very high risks of breast (80% by age 70 years) and ovarian cancer (15-40%). This justifies specific measures of screening, prevention and specific specialized care. The indications, methods and practical consequences of the diagnosis of a genetic predisposition are summarized, and specific care measures presented.

Translated title of the contribution	Genetic predisposition to breast and ovarian cancer: Molecular diagnosis and consequences
Original language	French
Pages (from-to)	213-218
Number of pages	6
Journal	Oncologie
Volume	8
Issue number	3
DOIs	https://doi.org/10.1007/s10269-006-0361-y
Publication status	Published - 1 Jan 2006

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abstract = "The molecular diagnosis of a genetic predisposition to breast cancer is now routinely available. BRCA1 and BRCA2 deleterious germline mutations confer very high risks of breast (80% by age 70 years) and ovarian cancer (15-40%). This justifies specific measures of screening, prevention and specific specialized care. The indications, methods and practical consequences of the diagnosis of a genetic predisposition are summarized, and specific care measures presented.",

keywords = "BRCA1, BRCA2, Breast cancer, Ovarian cancer, Predisposition",

author = "S. Delaloge and L. Albiges and {Bressac—de Paillerets}, B. and A. Chompret",

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T2 - Diagnostic moléculaire et conséquences

AU - Delaloge, S.

AU - Albiges, L.

AU - Bressac—de Paillerets, B.

AU - Chompret, A.

PY - 2006/1/1

Y1 - 2006/1/1

N2 - The molecular diagnosis of a genetic predisposition to breast cancer is now routinely available. BRCA1 and BRCA2 deleterious germline mutations confer very high risks of breast (80% by age 70 years) and ovarian cancer (15-40%). This justifies specific measures of screening, prevention and specific specialized care. The indications, methods and practical consequences of the diagnosis of a genetic predisposition are summarized, and specific care measures presented.

AB - The molecular diagnosis of a genetic predisposition to breast cancer is now routinely available. BRCA1 and BRCA2 deleterious germline mutations confer very high risks of breast (80% by age 70 years) and ovarian cancer (15-40%). This justifies specific measures of screening, prevention and specific specialized care. The indications, methods and practical consequences of the diagnosis of a genetic predisposition are summarized, and specific care measures presented.

KW - BRCA1

KW - BRCA2

KW - Breast cancer

KW - Ovarian cancer

KW - Predisposition

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U2 - 10.1007/s10269-006-0361-y

DO - 10.1007/s10269-006-0361-y

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EP - 218

JO - Oncologie

JF - Oncologie

IS - 3

ER -

Prédisposition génétique aux cancers du sein et de l'ovaire: Diagnostic moléculaire et conséquences

Abstract

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