Prevention and treatment of cancers by tumor antigen-expressing Staphylococcus epidermidis

Oliver Kepp; Laurence Zitvogel; Guido Kroemer

doi:10.1080/2162402X.2023.2212547

Prevention and treatment of cancers by tumor antigen-expressing Staphylococcus epidermidis

Oliver Kepp, Laurence Zitvogel, Guido Kroemer

Research output: Contribution to journal › Editorial

2 Citations (Scopus)

Abstract

In a recent paper in Science, Chen et al. reported the genetic engineering of S. epidermidis expressing tumor cross-reactive antigens that trigger T cell responses and exhibit anticancer effects after topical administration. Here we discuss direct local effects and indirect systemic effects of exposure to engineered S. epidermidis strains.

Original language	English
Article number	2212547
Journal	OncoImmunology
Volume	12
Issue number	1
DOIs	https://doi.org/10.1080/2162402X.2023.2212547
Publication status	Published - 1 Jan 2023

Keywords

Immunity
Immunotherapy
Microbiome

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10.1080/2162402X.2023.2212547

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title = "Prevention and treatment of cancers by tumor antigen-expressing Staphylococcus epidermidis",

abstract = "In a recent paper in Science, Chen et al. reported the genetic engineering of S. epidermidis expressing tumor cross-reactive antigens that trigger T cell responses and exhibit anticancer effects after topical administration. Here we discuss direct local effects and indirect systemic effects of exposure to engineered S. epidermidis strains.",

keywords = "Immunity, Immunotherapy, Microbiome",

author = "Oliver Kepp and Laurence Zitvogel and Guido Kroemer",

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AU - Zitvogel, Laurence

AU - Kroemer, Guido

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N2 - In a recent paper in Science, Chen et al. reported the genetic engineering of S. epidermidis expressing tumor cross-reactive antigens that trigger T cell responses and exhibit anticancer effects after topical administration. Here we discuss direct local effects and indirect systemic effects of exposure to engineered S. epidermidis strains.

AB - In a recent paper in Science, Chen et al. reported the genetic engineering of S. epidermidis expressing tumor cross-reactive antigens that trigger T cell responses and exhibit anticancer effects after topical administration. Here we discuss direct local effects and indirect systemic effects of exposure to engineered S. epidermidis strains.

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KW - Immunotherapy

KW - Microbiome

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JO - OncoImmunology

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Prevention and treatment of cancers by tumor antigen-expressing Staphylococcus epidermidis

Abstract

Keywords

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