Primary follicular lymphoma of the testis in children and adolescents

Mark A. Lones, Martine Raphael, Keith McCarthy, Andrew Wotherspoon, Marie Josee Terrier-Lacombe, Alan D. Ramsay, Ken MacLennan, Mitchell S. Cairo, Mary Gerrard, Jean Michon, Catherine Patte, Ross Pinkerton, Leonard Sender, Anne Auperin, Richard Sposto, Claire Weston, Nyla A. Heerema, Warren G. Sanger, Daniel Von Allmen, Sherrie L. Perkins

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    32 Citations (Scopus)

    Abstract

    This study reports 6 cases of primary follicular lymphoma of the testis (PFLT) in children and adolescents correlated with clinical presentation, pathologic features, treatment, and outcome. All 6 patients (age, 3 to 16 y; median, 4 y) had PFLT grade 3 with disease limited to the testis, completely resected and treated with 2 courses of chemotherapy (cyclophosphamide, vincristine, prednisone, doxorubicin). Event-free survival was 100% (follow-up: median, 73 mo; mean, 53 mo; range, 6 to 96 mo). In conclusion, clinical outcome in children and adolescents with PFLT is excellent with treatment including complete surgical resection and 2 courses of cyclophosphamide, vincristine, prednisone, doxorubicin.

    Original languageEnglish
    Pages (from-to)68-71
    Number of pages4
    JournalJournal of Pediatric Hematology/Oncology
    Volume34
    Issue number1
    DOIs
    Publication statusPublished - 1 Jan 2012

    Keywords

    • adolescence
    • child
    • lymphoma B-cell
    • lymphoma follicular
    • testis

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