Primitive neuroectodermal tumor of the myometrium with cardio-vascular symptoms

Olivier Mir; Laurence Albiges; Sylviane Arkwright; Denis Duboc; Pierre Philippe Massault; Florence Tenenbaum; Emmanuel Touzé; Philippe Menasché; Marie Cécile Vacher-Lavenu; François Goldwasser; Jérôme Alexandre

doi:10.1016/j.ygyno.2007.04.024

Primitive neuroectodermal tumor of the myometrium with cardio-vascular symptoms

Olivier Mir, Laurence Albiges, Sylviane Arkwright, Denis Duboc, Pierre Philippe Massault, Florence Tenenbaum, Emmanuel Touzé, Philippe Menasché, Marie Cécile Vacher-Lavenu, François Goldwasser, Jérôme Alexandre

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Background.: Non-bacterial thrombotic endocarditis is a severe complication of cancer, rarely reported in gynecologic tumors. However, it can be inaugural and lead to complex diagnostic pathways. Case.: A 40-year-old woman presented with a stroke, related to an endocarditis. The valvular vegetation was surgically removed, and a malignant node was resected. A PET-scan led to the diagnosis of a myometrial tumor, which was found to be a primitive neuroectodermal tumor (PNET). The patient underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy, and systemic chemotherapy which allowed a complete remission of tumoral and cardio-vascular symptoms. Conclusion.: To our knowledge, this is the first case report of a PNET of the myometrium revealed by cardio-vascular symptoms.

Original language	English
Pages (from-to)	622-625
Number of pages	4
Journal	Gynecologic Oncology
Volume	106
Issue number	3
DOIs	https://doi.org/10.1016/j.ygyno.2007.04.024
Publication status	Published - 1 Sept 2007
Externally published	Yes

Keywords

Endocarditis
PET scan
Primitive neuroectodermal tumor
Stroke

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10.1016/j.ygyno.2007.04.024

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title = "Primitive neuroectodermal tumor of the myometrium with cardio-vascular symptoms",

abstract = "Background.: Non-bacterial thrombotic endocarditis is a severe complication of cancer, rarely reported in gynecologic tumors. However, it can be inaugural and lead to complex diagnostic pathways. Case.: A 40-year-old woman presented with a stroke, related to an endocarditis. The valvular vegetation was surgically removed, and a malignant node was resected. A PET-scan led to the diagnosis of a myometrial tumor, which was found to be a primitive neuroectodermal tumor (PNET). The patient underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy, and systemic chemotherapy which allowed a complete remission of tumoral and cardio-vascular symptoms. Conclusion.: To our knowledge, this is the first case report of a PNET of the myometrium revealed by cardio-vascular symptoms.",

keywords = "Endocarditis, PET scan, Primitive neuroectodermal tumor, Stroke",

author = "Olivier Mir and Laurence Albiges and Sylviane Arkwright and Denis Duboc and Massault, {Pierre Philippe} and Florence Tenenbaum and Emmanuel Touz{\'e} and Philippe Menasch{\'e} and Vacher-Lavenu, {Marie C{\'e}cile} and Fran{\c c}ois Goldwasser and J{\'e}r{\^o}me Alexandre",

year = "2007",

month = sep,

day = "1",

doi = "10.1016/j.ygyno.2007.04.024",

language = "English",

volume = "106",

pages = "622--625",

journal = "Gynecologic Oncology",

issn = "0090-8258",

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T1 - Primitive neuroectodermal tumor of the myometrium with cardio-vascular symptoms

AU - Mir, Olivier

AU - Albiges, Laurence

AU - Arkwright, Sylviane

AU - Duboc, Denis

AU - Massault, Pierre Philippe

AU - Tenenbaum, Florence

AU - Touzé, Emmanuel

AU - Menasché, Philippe

AU - Vacher-Lavenu, Marie Cécile

AU - Goldwasser, François

AU - Alexandre, Jérôme

PY - 2007/9/1

Y1 - 2007/9/1

N2 - Background.: Non-bacterial thrombotic endocarditis is a severe complication of cancer, rarely reported in gynecologic tumors. However, it can be inaugural and lead to complex diagnostic pathways. Case.: A 40-year-old woman presented with a stroke, related to an endocarditis. The valvular vegetation was surgically removed, and a malignant node was resected. A PET-scan led to the diagnosis of a myometrial tumor, which was found to be a primitive neuroectodermal tumor (PNET). The patient underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy, and systemic chemotherapy which allowed a complete remission of tumoral and cardio-vascular symptoms. Conclusion.: To our knowledge, this is the first case report of a PNET of the myometrium revealed by cardio-vascular symptoms.

AB - Background.: Non-bacterial thrombotic endocarditis is a severe complication of cancer, rarely reported in gynecologic tumors. However, it can be inaugural and lead to complex diagnostic pathways. Case.: A 40-year-old woman presented with a stroke, related to an endocarditis. The valvular vegetation was surgically removed, and a malignant node was resected. A PET-scan led to the diagnosis of a myometrial tumor, which was found to be a primitive neuroectodermal tumor (PNET). The patient underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy, and systemic chemotherapy which allowed a complete remission of tumoral and cardio-vascular symptoms. Conclusion.: To our knowledge, this is the first case report of a PNET of the myometrium revealed by cardio-vascular symptoms.

KW - Endocarditis

KW - PET scan

KW - Primitive neuroectodermal tumor

KW - Stroke

UR - http://www.scopus.com/inward/record.url?scp=34548185690&partnerID=8YFLogxK

U2 - 10.1016/j.ygyno.2007.04.024

DO - 10.1016/j.ygyno.2007.04.024

M3 - Article

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AN - SCOPUS:34548185690

SN - 0090-8258

VL - 106

SP - 622

EP - 625

JO - Gynecologic Oncology

JF - Gynecologic Oncology

IS - 3

ER -

Primitive neuroectodermal tumor of the myometrium with cardio-vascular symptoms

Abstract

Keywords

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