Rôle du microbiote intestinal dans la réponse aux thérapies anti-tumorales

Translated title of the contribution: Gut microbiota and efficacy of cancer therapies

Marie Vétizou, Romain Daillère, Laurence Zitvogel

    Research output: Contribution to journalArticlepeer-review

    6 Citations (Scopus)

    Abstract

    The gut microbiota is known to affect digestion, protection against pathogens infection, immune system maturation and enteric nervous system development, but others links have also been established with diabetes, obesity, autism and cancer. Lately, bacterial species from the gut have been involved in tumor immunosurveillance. Natural or mediated by treatment such as chemotherapy or immunotherapy, anti-tumoral immune responses seem to rely on gut microbiota. The bacteria involved and their mechanisms of action are different according to the treatment of interest. Nevertheless, modulation of gut microbiota represents a great potential with the development of onco-micro-biotics to optimize the response to cancer therapies.

    Translated title of the contributionGut microbiota and efficacy of cancer therapies
    Original languageFrench
    Pages (from-to)51-67
    Number of pages17
    JournalBiologie Aujourd'hui
    Volume211
    Issue number1
    DOIs
    Publication statusPublished - 1 Jan 2017

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