Recommendations for stereotactic body radiation therapy for spine and non-spine bone metastases. A GETUG (French society of urological radiation oncolgists) consensus using a national two-round modified Delphi survey

F. Vilotte; D. Pasquier; P. Blanchard; S. Supiot; J. Khalifa; U. Schick; T. Lacornerie; L. Vieillevigne; D. Marre; O. Chapet; I. Latorzeff; N. Magne; E. Meyer; K. Cao; Y. Belkacemi; J. E. Bibault; M. Berge-Lefranc; J. C. Faivre; K. Gnep; V. Guimas; A. Hasbini; J. Langrand-Escure; C. Hennequin; P. Graff

doi:10.1016/j.ctro.2022.08.006

Recommendations for stereotactic body radiation therapy for spine and non-spine bone metastases. A GETUG (French society of urological radiation oncolgists) consensus using a national two-round modified Delphi survey

F. Vilotte, D. Pasquier, P. Blanchard, S. Supiot, J. Khalifa, U. Schick, T. Lacornerie, L. Vieillevigne, D. Marre, O. Chapet, I. Latorzeff, N. Magne, E. Meyer, K. Cao, Y. Belkacemi, J. E. Bibault, M. Berge-Lefranc, J. C. Faivre, K. Gnep, V. GuimasA. Hasbini, J. Langrand-Escure, C. Hennequin, P. Graff

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Background and purpose: The relevance of metastasis-directed stereotactic body radiation therapy (SBRT) remains to be demonstrated through phase III trials. Multiple SBRT procedures have been published potentially resulting in a disparity of practices. Therefore, the french society of urological radiation oncolgists (GETUG) recognized the need for joint expert consensus guidelines for metastasis-directed SBRT in order to standardize practice in trials carried out by the group. Materials and methods: After a comprehensive literature review, 97 recommendation statements were created regarding planning and delivery of spine bone (SBM) and non-spine bone metastases (NSBM) SBRT. These statements were then submitted to a national online two-round modified Delphi survey among main GETUG investigators. Consensus was achieved if a statement received ≥ 75 % agreements, a trend to consensus being defined as 65–74 % agreements. Any statement without consensus at round one was re-submitted in round two. Results: Twenty-one out of 29 (72.4%) surveyed experts responded to both rounds. Seventy-five statements achieved consensus at round one leaving 22 statements needing a revote of which 16 achieved consensus and 5 a trend to consensus. The final rate of consensus was 91/97 (93.8%). Statements with no consensus concerned patient selection (3/19), dose and fractionation (1/11), prescription and dose objectives (1/9) and organs at risk delineation (1/15). The voting resulted in the writing of step-by-step consensus guidelines. Conclusion: Consensus guidelines for SBM and NSBM SBRT were agreed upon using a validated modified Delphi approach. These guidelines will be used as per-protocole recommendations in ongoing and further GETUG clinical trials.

Original language	English
Pages (from-to)	33-40
Number of pages	8
Journal	Clinical and Translational Radiation Oncology
Volume	37
DOIs	https://doi.org/10.1016/j.ctro.2022.08.006
Publication status	Published - 1 Nov 2022

Keywords

Metastasis-directed
Non-spine bone metastasis
Oligometastatic
Spine bone metastasis
Stereotactic radiation therapy
Stereotaxy

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10.1016/j.ctro.2022.08.006

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Vilotte, F., Pasquier, D., Blanchard, P., Supiot, S., Khalifa, J., Schick, U., Lacornerie, T., Vieillevigne, L., Marre, D., Chapet, O., Latorzeff, I., Magne, N., Meyer, E., Cao, K., Belkacemi, Y., Bibault, J. E., Berge-Lefranc, M., Faivre, J. C., Gnep, K., ... Graff, P. (2022). Recommendations for stereotactic body radiation therapy for spine and non-spine bone metastases. A GETUG (French society of urological radiation oncolgists) consensus using a national two-round modified Delphi survey. Clinical and Translational Radiation Oncology, 37, 33-40. https://doi.org/10.1016/j.ctro.2022.08.006

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title = "Recommendations for stereotactic body radiation therapy for spine and non-spine bone metastases. A GETUG (French society of urological radiation oncolgists) consensus using a national two-round modified Delphi survey",

abstract = "Background and purpose: The relevance of metastasis-directed stereotactic body radiation therapy (SBRT) remains to be demonstrated through phase III trials. Multiple SBRT procedures have been published potentially resulting in a disparity of practices. Therefore, the french society of urological radiation oncolgists (GETUG) recognized the need for joint expert consensus guidelines for metastasis-directed SBRT in order to standardize practice in trials carried out by the group. Materials and methods: After a comprehensive literature review, 97 recommendation statements were created regarding planning and delivery of spine bone (SBM) and non-spine bone metastases (NSBM) SBRT. These statements were then submitted to a national online two-round modified Delphi survey among main GETUG investigators. Consensus was achieved if a statement received ≥ 75 % agreements, a trend to consensus being defined as 65–74 % agreements. Any statement without consensus at round one was re-submitted in round two. Results: Twenty-one out of 29 (72.4%) surveyed experts responded to both rounds. Seventy-five statements achieved consensus at round one leaving 22 statements needing a revote of which 16 achieved consensus and 5 a trend to consensus. The final rate of consensus was 91/97 (93.8%). Statements with no consensus concerned patient selection (3/19), dose and fractionation (1/11), prescription and dose objectives (1/9) and organs at risk delineation (1/15). The voting resulted in the writing of step-by-step consensus guidelines. Conclusion: Consensus guidelines for SBM and NSBM SBRT were agreed upon using a validated modified Delphi approach. These guidelines will be used as per-protocole recommendations in ongoing and further GETUG clinical trials.",

keywords = "Metastasis-directed, Non-spine bone metastasis, Oligometastatic, Spine bone metastasis, Stereotactic radiation therapy, Stereotaxy",

author = "F. Vilotte and D. Pasquier and P. Blanchard and S. Supiot and J. Khalifa and U. Schick and T. Lacornerie and L. Vieillevigne and D. Marre and O. Chapet and I. Latorzeff and N. Magne and E. Meyer and K. Cao and Y. Belkacemi and Bibault, {J. E.} and M. Berge-Lefranc and Faivre, {J. C.} and K. Gnep and V. Guimas and A. Hasbini and J. Langrand-Escure and C. Hennequin and P. Graff",

note = "Publisher Copyright: {\textcopyright} 2022 The Authors",

year = "2022",

month = nov,

day = "1",

doi = "10.1016/j.ctro.2022.08.006",

language = "English",

volume = "37",

pages = "33--40",

journal = "Clinical and Translational Radiation Oncology",

issn = "2405-6308",

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Vilotte, F, Pasquier, D, Blanchard, P, Supiot, S, Khalifa, J, Schick, U, Lacornerie, T, Vieillevigne, L, Marre, D, Chapet, O, Latorzeff, I, Magne, N, Meyer, E, Cao, K, Belkacemi, Y, Bibault, JE, Berge-Lefranc, M, Faivre, JC, Gnep, K, Guimas, V, Hasbini, A, Langrand-Escure, J, Hennequin, C & Graff, P 2022, 'Recommendations for stereotactic body radiation therapy for spine and non-spine bone metastases. A GETUG (French society of urological radiation oncolgists) consensus using a national two-round modified Delphi survey', Clinical and Translational Radiation Oncology, vol. 37, pp. 33-40. https://doi.org/10.1016/j.ctro.2022.08.006

Recommendations for stereotactic body radiation therapy for spine and non-spine bone metastases. A GETUG (French society of urological radiation oncolgists) consensus using a national two-round modified Delphi survey. / Vilotte, F.; Pasquier, D.; Blanchard, P. et al.
In: Clinical and Translational Radiation Oncology, Vol. 37, 01.11.2022, p. 33-40.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Recommendations for stereotactic body radiation therapy for spine and non-spine bone metastases. A GETUG (French society of urological radiation oncolgists) consensus using a national two-round modified Delphi survey

AU - Vilotte, F.

AU - Pasquier, D.

AU - Blanchard, P.

AU - Supiot, S.

AU - Khalifa, J.

AU - Schick, U.

AU - Lacornerie, T.

AU - Vieillevigne, L.

AU - Marre, D.

AU - Chapet, O.

AU - Latorzeff, I.

AU - Magne, N.

AU - Meyer, E.

AU - Cao, K.

AU - Belkacemi, Y.

AU - Bibault, J. E.

AU - Berge-Lefranc, M.

AU - Faivre, J. C.

AU - Gnep, K.

AU - Guimas, V.

AU - Hasbini, A.

AU - Langrand-Escure, J.

AU - Hennequin, C.

AU - Graff, P.

PY - 2022/11/1

Y1 - 2022/11/1

N2 - Background and purpose: The relevance of metastasis-directed stereotactic body radiation therapy (SBRT) remains to be demonstrated through phase III trials. Multiple SBRT procedures have been published potentially resulting in a disparity of practices. Therefore, the french society of urological radiation oncolgists (GETUG) recognized the need for joint expert consensus guidelines for metastasis-directed SBRT in order to standardize practice in trials carried out by the group. Materials and methods: After a comprehensive literature review, 97 recommendation statements were created regarding planning and delivery of spine bone (SBM) and non-spine bone metastases (NSBM) SBRT. These statements were then submitted to a national online two-round modified Delphi survey among main GETUG investigators. Consensus was achieved if a statement received ≥ 75 % agreements, a trend to consensus being defined as 65–74 % agreements. Any statement without consensus at round one was re-submitted in round two. Results: Twenty-one out of 29 (72.4%) surveyed experts responded to both rounds. Seventy-five statements achieved consensus at round one leaving 22 statements needing a revote of which 16 achieved consensus and 5 a trend to consensus. The final rate of consensus was 91/97 (93.8%). Statements with no consensus concerned patient selection (3/19), dose and fractionation (1/11), prescription and dose objectives (1/9) and organs at risk delineation (1/15). The voting resulted in the writing of step-by-step consensus guidelines. Conclusion: Consensus guidelines for SBM and NSBM SBRT were agreed upon using a validated modified Delphi approach. These guidelines will be used as per-protocole recommendations in ongoing and further GETUG clinical trials.

AB - Background and purpose: The relevance of metastasis-directed stereotactic body radiation therapy (SBRT) remains to be demonstrated through phase III trials. Multiple SBRT procedures have been published potentially resulting in a disparity of practices. Therefore, the french society of urological radiation oncolgists (GETUG) recognized the need for joint expert consensus guidelines for metastasis-directed SBRT in order to standardize practice in trials carried out by the group. Materials and methods: After a comprehensive literature review, 97 recommendation statements were created regarding planning and delivery of spine bone (SBM) and non-spine bone metastases (NSBM) SBRT. These statements were then submitted to a national online two-round modified Delphi survey among main GETUG investigators. Consensus was achieved if a statement received ≥ 75 % agreements, a trend to consensus being defined as 65–74 % agreements. Any statement without consensus at round one was re-submitted in round two. Results: Twenty-one out of 29 (72.4%) surveyed experts responded to both rounds. Seventy-five statements achieved consensus at round one leaving 22 statements needing a revote of which 16 achieved consensus and 5 a trend to consensus. The final rate of consensus was 91/97 (93.8%). Statements with no consensus concerned patient selection (3/19), dose and fractionation (1/11), prescription and dose objectives (1/9) and organs at risk delineation (1/15). The voting resulted in the writing of step-by-step consensus guidelines. Conclusion: Consensus guidelines for SBM and NSBM SBRT were agreed upon using a validated modified Delphi approach. These guidelines will be used as per-protocole recommendations in ongoing and further GETUG clinical trials.

KW - Metastasis-directed

KW - Non-spine bone metastasis

KW - Oligometastatic

KW - Spine bone metastasis

KW - Stereotactic radiation therapy

KW - Stereotaxy

UR - http://www.scopus.com/inward/record.url?scp=85136455552&partnerID=8YFLogxK

U2 - 10.1016/j.ctro.2022.08.006

DO - 10.1016/j.ctro.2022.08.006

M3 - Article

AN - SCOPUS:85136455552

SN - 2405-6308

VL - 37

SP - 33

EP - 40

JO - Clinical and Translational Radiation Oncology

JF - Clinical and Translational Radiation Oncology

ER -

Vilotte F, Pasquier D, Blanchard P, Supiot S, Khalifa J, Schick U et al. Recommendations for stereotactic body radiation therapy for spine and non-spine bone metastases. A GETUG (French society of urological radiation oncolgists) consensus using a national two-round modified Delphi survey. Clinical and Translational Radiation Oncology. 2022 Nov 1;37:33-40. doi: 10.1016/j.ctro.2022.08.006

Recommendations for stereotactic body radiation therapy for spine and non-spine bone metastases. A GETUG (French society of urological radiation oncolgists) consensus using a national two-round modified Delphi survey

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Keywords

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