Results of interval debulking surgery in advanced stage ovarian cancer: An exposed-non-exposed study

P. Morice; D. Brehier-Ollive; A. Rey; D. Atallah; C. Lhommé; P. Pautier; C. Pomel; S. Camatte; P. Duvillard; D. Castaigne

doi:10.1093/annonc/mdg003

Results of interval debulking surgery in advanced stage ovarian cancer: An exposed-non-exposed study

P. Morice, D. Brehier-Ollive, A. Rey, D. Atallah, C. Lhommé, P. Pautier, C. Pomel, S. Camatte, P. Duvillard, D. Castaigne

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67 Citations (Scopus)

Abstract

Background: To study the results of interval debulking surgery (IDS) in patients treated for 'unresectable' advanced stage ovarian cancer compared with primary debulking surgery (PDS) followed by chemotherapy. Patients and methods: An exposed-non-exposed study including a group of 34 patients who underwent an IDS and were matched to an historic control group of 34 patients treated with PDS. Results: Optimal cytoreductive surgery was achieved in 94% (32 out of 34) of patients in both groups. The rates of post-operative morbidity, blood transfusion and median length of hospitalisation were significantly reduced in the study (IDS) group, but survival did not differ in both groups. Conclusions: IDS in patients with advanced stage ovarian cancer offers the same chance of survival as PDS, but it is better tolerated.

Original language	English
Pages (from-to)	74-77
Number of pages	4
Journal	Annals of Oncology
Volume	14
Issue number	1
DOIs	https://doi.org/10.1093/annonc/mdg003
Publication status	Published - 1 Jan 2003

Keywords

Induction chemotherapy
Interval debulking surgery
Ovarian cancer
Unresectable tumour

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10.1093/annonc/mdg003

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abstract = "Background: To study the results of interval debulking surgery (IDS) in patients treated for 'unresectable' advanced stage ovarian cancer compared with primary debulking surgery (PDS) followed by chemotherapy. Patients and methods: An exposed-non-exposed study including a group of 34 patients who underwent an IDS and were matched to an historic control group of 34 patients treated with PDS. Results: Optimal cytoreductive surgery was achieved in 94% (32 out of 34) of patients in both groups. The rates of post-operative morbidity, blood transfusion and median length of hospitalisation were significantly reduced in the study (IDS) group, but survival did not differ in both groups. Conclusions: IDS in patients with advanced stage ovarian cancer offers the same chance of survival as PDS, but it is better tolerated.",

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AU - Morice, P.

AU - Brehier-Ollive, D.

AU - Rey, A.

AU - Atallah, D.

AU - Lhommé, C.

AU - Pautier, P.

AU - Pomel, C.

AU - Camatte, S.

AU - Duvillard, P.

AU - Castaigne, D.

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KW - Induction chemotherapy

KW - Interval debulking surgery

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KW - Unresectable tumour

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Results of interval debulking surgery in advanced stage ovarian cancer: An exposed-non-exposed study

Abstract

Keywords

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