Risk-oriented concept of treatment for intrathyroid papillary thyroid cancer

Dana M. Hartl, Julien Hadoux, Joanne Guerlain, Ingrid Breuskin, Fabienne Haroun, Sophie Bidault, Sophie Leboulleux, Livia Lamartina

    Research output: Contribution to journalReview articlepeer-review

    17 Citations (Scopus)

    Abstract

    Adapting treatment and follow-up according to the risk of recurrence and/or death from thyroid cancer is a relatively recent concept of “personnalized” medicine, developed particularly to avoid overtreatment of low-risk thyroid cancer which represents the majority of thyroid cancers diagnosed in the world today. For low-risk thyroid cancer, this decrease in extent of treatment involves the extent of surgery—total thyroidectomy, lobectomy or no surgery with active surveillance—but also the indications, doses and methods of stimulation when or if administering radioactive iodine (RAI), the indication for suppressive thyroxin therapy and the extent and modalities for follow-up that should be adapted to the risk of recurrence. The aim is to optimize medical resources and quality of life, particularly for low-risk patients whose life expectancy is that of the general population.

    Original languageEnglish
    Article number101281
    JournalBest Practice and Research: Clinical Endocrinology and Metabolism
    Volume33
    Issue number4
    DOIs
    Publication statusPublished - 1 Aug 2019

    Keywords

    • active surveillance
    • dynamic risk assessment
    • thyroid cancer

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