Sequential blinded treatment decisions in ALK-positive non-small cell lung cancers in the era of precision medicine

J. Remon; F. Tabbò; B. Jimenez; A. Collazo; J. de Castro; S. Novello

doi:10.1007/s12094-020-02290-1

Sequential blinded treatment decisions in ALK-positive non-small cell lung cancers in the era of precision medicine

J. Remon, F. Tabbò, B. Jimenez, A. Collazo, J. de Castro, S. Novello

Research output: Contribution to journal › Review article › peer-review

8 Citations (Scopus)

Abstract

Next-generation ALK TKIs have become the new standard of care in first-line setting in advanced ALK-positive NSCLC patients. However, sequential strategies at progression are relevant, as may have an impact on patients’ outcome. In this commentary we discuss whether genomic-tailored strategies at progression would be more suitable for improving outcome of ALK-positive NSCLC patients.

Original language	English
Pages (from-to)	1425-1429
Number of pages	5
Journal	Clinical and Translational Oncology
Volume	22
Issue number	9
DOIs	https://doi.org/10.1007/s12094-020-02290-1
Publication status	Published - 1 Sept 2020
Externally published	Yes

Keywords

ALK
Liquid biopsy
Next-generation
Non-small cell lung cancer
Sequential treatment

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10.1007/s12094-020-02290-1

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title = "Sequential blinded treatment decisions in ALK-positive non-small cell lung cancers in the era of precision medicine",

abstract = "Next-generation ALK TKIs have become the new standard of care in first-line setting in advanced ALK-positive NSCLC patients. However, sequential strategies at progression are relevant, as may have an impact on patients{\textquoteright} outcome. In this commentary we discuss whether genomic-tailored strategies at progression would be more suitable for improving outcome of ALK-positive NSCLC patients.",

keywords = "ALK, Liquid biopsy, Next-generation, Non-small cell lung cancer, Sequential treatment",

author = "J. Remon and F. Tabb{\`o} and B. Jimenez and A. Collazo and {de Castro}, J. and S. Novello",

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AU - Remon, J.

AU - Tabbò, F.

AU - Jimenez, B.

AU - Collazo, A.

AU - de Castro, J.

AU - Novello, S.

PY - 2020/9/1

Y1 - 2020/9/1

N2 - Next-generation ALK TKIs have become the new standard of care in first-line setting in advanced ALK-positive NSCLC patients. However, sequential strategies at progression are relevant, as may have an impact on patients’ outcome. In this commentary we discuss whether genomic-tailored strategies at progression would be more suitable for improving outcome of ALK-positive NSCLC patients.

AB - Next-generation ALK TKIs have become the new standard of care in first-line setting in advanced ALK-positive NSCLC patients. However, sequential strategies at progression are relevant, as may have an impact on patients’ outcome. In this commentary we discuss whether genomic-tailored strategies at progression would be more suitable for improving outcome of ALK-positive NSCLC patients.

KW - ALK

KW - Liquid biopsy

KW - Next-generation

KW - Non-small cell lung cancer

KW - Sequential treatment

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U2 - 10.1007/s12094-020-02290-1

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M3 - Review article

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AN - SCOPUS:85078289456

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JO - Clinical and Translational Oncology

JF - Clinical and Translational Oncology

IS - 9

ER -

Sequential blinded treatment decisions in ALK-positive non-small cell lung cancers in the era of precision medicine

Abstract

Keywords

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