Using the Human Plasma PeptideAtlas to Study Human Plasma Proteins

Terry Farrah, Eric W. Deutsch, Ruedi Aebersold

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

23 Citations (Scopus)

Abstract

PeptideAtlas is a web-accessible database of LC–MS/MS shotgun proteomics results from hundreds of experiments conducted in diverse laboratories, with all data processed via a uniform analysis pipeline. A total of 91 experiments on human plasma and serum are included. Using the PeptideAtlas web interface, users can browse and search the Human Plasma PeptideAtlas for identified peptides and identified proteins, view spectra, and select proteotypic peptides. Users can easily view supporting information such as chromosomal mapping, estimated abundances, and sequence alignments. Herein, the reader is instructed in the use of the Human Plasma PeptideAtlas through an illustrated exploration of cytokine receptors in plasma.

Original languageEnglish
Title of host publicationSerum/Plasma Proteomics
Subtitle of host publicationMethods and Protocols
PublisherHumana Press Inc.
Pages349-374
Number of pages26
ISBN (Print)9781617790676
DOIs
Publication statusPublished - 1 Jan 2011
Externally publishedYes

Publication series

NameMethods in Molecular Biology
Volume728
ISSN (Print)1064-3745
ISSN (Electronic)1940-6029

Keywords

  • PeptideAtlas
  • Plasma

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