Using the Human Plasma PeptideAtlas to Study Human Plasma Proteins

Terry Farrah, Eric W. Deutsch, Ruedi Aebersold

    Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

    25 Citations (Scopus)

    Abstract

    PeptideAtlas is a web-accessible database of LC–MS/MS shotgun proteomics results from hundreds of experiments conducted in diverse laboratories, with all data processed via a uniform analysis pipeline. A total of 91 experiments on human plasma and serum are included. Using the PeptideAtlas web interface, users can browse and search the Human Plasma PeptideAtlas for identified peptides and identified proteins, view spectra, and select proteotypic peptides. Users can easily view supporting information such as chromosomal mapping, estimated abundances, and sequence alignments. Herein, the reader is instructed in the use of the Human Plasma PeptideAtlas through an illustrated exploration of cytokine receptors in plasma.

    Original languageEnglish
    Title of host publicationSerum/Plasma Proteomics
    Subtitle of host publicationMethods and Protocols
    PublisherHumana Press Inc.
    Pages349-374
    Number of pages26
    ISBN (Print)9781617790676
    DOIs
    Publication statusPublished - 1 Jan 2011

    Publication series

    NameMethods in Molecular Biology
    Volume728
    ISSN (Print)1064-3745
    ISSN (Electronic)1940-6029

    Keywords

    • PeptideAtlas
    • Plasma

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