Wound healing delay after central venous access following DCF/VEGF-trap therapy

Charles Ferté; Christophe Massard; Christian Moldovan; Eric Desruennes; Yohann Loriot; Jean Charles Soria

doi:10.1007/s10637-009-9227-7

Wound healing delay after central venous access following DCF/VEGF-trap therapy

Charles Ferté, Christophe Massard, Christian Moldovan, Eric Desruennes, Yohann Loriot, Jean Charles Soria

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Summary: Hypertension, proteinuria, thromboembolic or bleeding events are well-recognized complications occurring while targeting VEGF pathway. Wound healing dysfunctions have also been described in patients undergoing major surgery. For the first time, we report wound healing delay after central venous access following DCF-VEGF-Trap. VEGF-Trap may affect both angiogenesis and reepithelialization which are necessary to the normal repair process.

Original language	English
Pages (from-to)	583-585
Number of pages	3
Journal	Investigational New Drugs
Volume	27
Issue number	6
DOIs	https://doi.org/10.1007/s10637-009-9227-7
Publication status	Published - 1 Dec 2009

Keywords

Central venous access
VEGF-Trap
Wound healing

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10.1007/s10637-009-9227-7

Cite this

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abstract = "Summary: Hypertension, proteinuria, thromboembolic or bleeding events are well-recognized complications occurring while targeting VEGF pathway. Wound healing dysfunctions have also been described in patients undergoing major surgery. For the first time, we report wound healing delay after central venous access following DCF-VEGF-Trap. VEGF-Trap may affect both angiogenesis and reepithelialization which are necessary to the normal repair process.",

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AU - Ferté, Charles

AU - Massard, Christophe

AU - Moldovan, Christian

AU - Desruennes, Eric

AU - Loriot, Yohann

AU - Soria, Jean Charles

PY - 2009/12/1

Y1 - 2009/12/1

N2 - Summary: Hypertension, proteinuria, thromboembolic or bleeding events are well-recognized complications occurring while targeting VEGF pathway. Wound healing dysfunctions have also been described in patients undergoing major surgery. For the first time, we report wound healing delay after central venous access following DCF-VEGF-Trap. VEGF-Trap may affect both angiogenesis and reepithelialization which are necessary to the normal repair process.

AB - Summary: Hypertension, proteinuria, thromboembolic or bleeding events are well-recognized complications occurring while targeting VEGF pathway. Wound healing dysfunctions have also been described in patients undergoing major surgery. For the first time, we report wound healing delay after central venous access following DCF-VEGF-Trap. VEGF-Trap may affect both angiogenesis and reepithelialization which are necessary to the normal repair process.

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KW - Wound healing

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Wound healing delay after central venous access following DCF/VEGF-trap therapy

Abstract

Keywords

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