A guided tour of the Trans-Proteomic Pipeline

Eric W. Deutsch; Luis Mendoza; David Shteynberg; Terry Farrah; Henry Lam; Natalie Tasman; Zhi Sun; Erik Nilsson; Brian Pratt; Bryan Prazen; Jimmy K. Eng; Daniel B. Martin; Alexey I. Nesvizhskii; Ruedi Aebersold

doi:10.1002/pmic.200900375

A guided tour of the Trans-Proteomic Pipeline

Eric W. Deutsch, Luis Mendoza, David Shteynberg, Terry Farrah, Henry Lam, Natalie Tasman, Zhi Sun, Erik Nilsson, Brian Pratt, Bryan Prazen, Jimmy K. Eng, Daniel B. Martin, Alexey I. Nesvizhskii, Ruedi Aebersold

Résultats de recherche: Contribution à un journal › Article 'review' › Revue par des pairs

636 Citations (Scopus)

Résumé

The Trans-Proteomic Pipeline (TPP) is a suite of software tools for the analysis of MS/MS data sets. The tools encompass most of the steps in a proteomic data analysis workflow in a single, integrated software system. Specifically, the TPP supports all steps from spectrometer output file conversion to protein-level statistical validation, including quantification by stable isotope ratios. We describe here the full workflow of the TPP and the tools therein, along with an example on a sample data set, demonstrating that the setup and use of the tools are straightforward and well supported and do not require specialized informatic resources or knowledge.

langue originale	Anglais
Pages (de - à)	1150-1159
Nombre de pages	10
journal	Proteomics
Volume	10
Numéro de publication	6
Les DOIs	https://doi.org/10.1002/pmic.200900375
état	Publié - 1 mars 2010
Modification externe	Oui

Accès au document

10.1002/pmic.200900375

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AU - Mendoza, Luis

AU - Shteynberg, David

AU - Farrah, Terry

AU - Lam, Henry

AU - Tasman, Natalie

AU - Sun, Zhi

AU - Nilsson, Erik

AU - Pratt, Brian

AU - Prazen, Bryan

AU - Eng, Jimmy K.

AU - Martin, Daniel B.

AU - Nesvizhskii, Alexey I.

AU - Aebersold, Ruedi

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