A monoclonal antibody reacting with a membrane determinant expressed on activated chicken T lymphocytes

Karel Hála, Konrad Schauenstein, Nikolaus Neu, Guido Krömer, Hugo Wolf, Günther Böck, Georg Wick

Résultats de recherche: Contribution à un journalArticleRevue par des pairs

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Résumé

A monoclonal antibody (INN‐CH‐16) was prepared which reacts with a cell surface antigen termed chicken activated T lymphocyte antigen. This antigen is expressed on antigen‐ or mitogen‐activated T lymphocytes and is not present on nonstimulated lymphocytes. It has an apparent molecular mass of 48‐50 kDa under reducing conditions. The value of this antibody for the immunohistochemical characterization of infiltrating cells in the thyroid glands from Obese strain chickens with spontaneous thyroiditis is demonstrated.

langue originaleAnglais
Pages (de - à)1331-1336
Nombre de pages6
journalEuropean Journal of Immunology
Volume16
Numéro de publication11
Les DOIs
étatPublié - 1 janv. 1986
Modification externeOui

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