Abnormal cytogenetics and significant bone marrow plasmacytosis are predictive of early progression and short survival in patients with low tumor mass asymptomatic multiple myeloma

Stephane Depil; Xavier Leleu; Jean Baptiste Micol; Celine Berthon; Jean Luc Laï; Francis Bauters; Bruno Quesnel; Thierry Facon

doi:10.1080/10428190412331283224

Abnormal cytogenetics and significant bone marrow plasmacytosis are predictive of early progression and short survival in patients with low tumor mass asymptomatic multiple myeloma

Stephane Depil, Xavier Leleu, Jean Baptiste Micol, Celine Berthon, Jean Luc Laï, Francis Bauters, Bruno Quesnel, Thierry Facon

Résultats de recherche: Contribution à un journal › Article › Revue par des pairs

10 Citations (Scopus)

Résumé

In order to evaluate the prognostic factors for progression and survival in patients with a low tumor mass asymptomatic multiple myeloma (MM), we studied 59 patients who had a long term follow-up. Cytogenetic abnormalities (using conventional cytogenetics) were observed in 14 out of 45 analyzable patients (31%). An abnormal karyotype and a bone marrow (BM) plasmacytosis > 15% were found to be adverse prognostic factors for progression in univariate and multivariate analysis.

langue originale	Anglais
Pages (de - à)	2481-2484
Nombre de pages	4
journal	Leukemia and Lymphoma
Volume	45
Numéro de publication	12
Les DOIs	https://doi.org/10.1080/10428190412331283224
état	Publié - 1 déc. 2004
Modification externe	Oui

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10.1080/10428190412331283224

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Depil, S., Leleu, X., Micol, J. B., Berthon, C., Laï, J. L., Bauters, F., Quesnel, B., & Facon, T. (2004). Abnormal cytogenetics and significant bone marrow plasmacytosis are predictive of early progression and short survival in patients with low tumor mass asymptomatic multiple myeloma. Leukemia and Lymphoma, 45(12), 2481-2484. https://doi.org/10.1080/10428190412331283224

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title = "Abnormal cytogenetics and significant bone marrow plasmacytosis are predictive of early progression and short survival in patients with low tumor mass asymptomatic multiple myeloma",

abstract = "In order to evaluate the prognostic factors for progression and survival in patients with a low tumor mass asymptomatic multiple myeloma (MM), we studied 59 patients who had a long term follow-up. Cytogenetic abnormalities (using conventional cytogenetics) were observed in 14 out of 45 analyzable patients (31%). An abnormal karyotype and a bone marrow (BM) plasmacytosis > 15% were found to be adverse prognostic factors for progression in univariate and multivariate analysis.",

keywords = "Karyotype, Multiple myeloma, Prognosis",

author = "Stephane Depil and Xavier Leleu and Micol, {Jean Baptiste} and Celine Berthon and La{\"i}, {Jean Luc} and Francis Bauters and Bruno Quesnel and Thierry Facon",

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Depil, S, Leleu, X, Micol, JB, Berthon, C, Laï, JL, Bauters, F, Quesnel, B & Facon, T 2004, 'Abnormal cytogenetics and significant bone marrow plasmacytosis are predictive of early progression and short survival in patients with low tumor mass asymptomatic multiple myeloma', Leukemia and Lymphoma, VOL. 45, Numéro 12, p. 2481-2484. https://doi.org/10.1080/10428190412331283224

Abnormal cytogenetics and significant bone marrow plasmacytosis are predictive of early progression and short survival in patients with low tumor mass asymptomatic multiple myeloma. / Depil, Stephane; Leleu, Xavier; Micol, Jean Baptiste et al.
Dans: Leukemia and Lymphoma, Vol 45, Numéro 12, 01.12.2004, p. 2481-2484.

Résultats de recherche: Contribution à un journal › Article › Revue par des pairs

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T1 - Abnormal cytogenetics and significant bone marrow plasmacytosis are predictive of early progression and short survival in patients with low tumor mass asymptomatic multiple myeloma

AU - Depil, Stephane

AU - Leleu, Xavier

AU - Micol, Jean Baptiste

AU - Berthon, Celine

AU - Laï, Jean Luc

AU - Bauters, Francis

AU - Quesnel, Bruno

AU - Facon, Thierry

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N2 - In order to evaluate the prognostic factors for progression and survival in patients with a low tumor mass asymptomatic multiple myeloma (MM), we studied 59 patients who had a long term follow-up. Cytogenetic abnormalities (using conventional cytogenetics) were observed in 14 out of 45 analyzable patients (31%). An abnormal karyotype and a bone marrow (BM) plasmacytosis > 15% were found to be adverse prognostic factors for progression in univariate and multivariate analysis.

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