TY - JOUR
T1 - About a case of primary laryngeal mucosal melanoma in a patient with medical history of oropharyngeal squamous carcinoma
AU - Michaut, Alice
AU - Clair, Guillaume
AU - Hanau, Edouard
AU - Ratour, Julia
AU - Laccoureye, Ollivier
AU - Badoual, Cécile
N1 - Publisher Copyright:
© 2024 Elsevier Masson SAS
PY - 2024/1/1
Y1 - 2024/1/1
N2 - Introduction: Primary laryngeal mucosal melanoma is a rare tumour with a poor prognosis. Its often difficult diagnosis should rule out laryngeal metastatic localization of cutaneous melanoma. Case presentation: We report a case of primary laryngeal mucosal melanoma diagnosed in a 65-year-old man, treated 6 years previously with radio-chemotherapy and surgery for squamous cell carcinoma of the right lateral oropharyngeal region. The definitive diagnosis of primary laryngeal mucosal melanoma was made on the resection specimen, whereas the initial biopsy of the epilaryngeal mass discovered during the patient's surveillance had concluded that it was a laryngeal recurrence of the known squamous cell carcinoma. Discussion: Through this case, we propose to remind the main characteristics and the diagnostic pitfalls of these tumours.
AB - Introduction: Primary laryngeal mucosal melanoma is a rare tumour with a poor prognosis. Its often difficult diagnosis should rule out laryngeal metastatic localization of cutaneous melanoma. Case presentation: We report a case of primary laryngeal mucosal melanoma diagnosed in a 65-year-old man, treated 6 years previously with radio-chemotherapy and surgery for squamous cell carcinoma of the right lateral oropharyngeal region. The definitive diagnosis of primary laryngeal mucosal melanoma was made on the resection specimen, whereas the initial biopsy of the epilaryngeal mass discovered during the patient's surveillance had concluded that it was a laryngeal recurrence of the known squamous cell carcinoma. Discussion: Through this case, we propose to remind the main characteristics and the diagnostic pitfalls of these tumours.
KW - ENT cancer
KW - Laryngeal epithelium
KW - Melanoma
KW - Mucosal melanoma
KW - Second primary cancer
UR - http://www.scopus.com/inward/record.url?scp=85195038954&partnerID=8YFLogxK
U2 - 10.1016/j.annpat.2024.04.017
DO - 10.1016/j.annpat.2024.04.017
M3 - Article
AN - SCOPUS:85195038954
SN - 0242-6498
JO - Annales de Pathologie
JF - Annales de Pathologie
ER -