Résumé
Cytokinesis the final step of mitosis in which the two daughter cells separate requires accumulation of specific proteins and lipids at the connecting bridge to ensure cleavage by abscission. Phosphatidylinositol-3-phosphate (PtdIns(3)P), an endosomal phosphoinositide, and FYVE-CENT, a PtdIns3P-binding protein, are found in the bridge, where they contribute to the mechanism of abscission.
langue originale | Anglais |
---|---|
Pages (de - à) | 308-310 |
Nombre de pages | 3 |
journal | Nature Cell Biology |
Volume | 12 |
Numéro de publication | 4 |
Les DOIs | |
état | Publié - 1 avr. 2010 |