Analysis of the Saccharomyces cerevisiae proteome with PeptideAtlas

Nichole L. King; Eric W. Deutsch; Jeffrey A. Ranish; Alexey I. Nesvizhskii; James S. Eddes; Parag Mallick; Jimmy Eng; Frank Desiere; Mark Flory; Daniel B. Martin; Bong Kim; Hookeun Lee; Brian Raught; Ruedi Aebersold

doi:10.1186/gb-2006-7-11-r106

Analysis of the Saccharomyces cerevisiae proteome with PeptideAtlas

Nichole L. King, Eric W. Deutsch, Jeffrey A. Ranish, Alexey I. Nesvizhskii, James S. Eddes, Parag Mallick, Jimmy Eng, Frank Desiere, Mark Flory, Daniel B. Martin, Bong Kim, Hookeun Lee, Brian Raught, Ruedi Aebersold

Résultats de recherche: Contribution à un journal › Article › Revue par des pairs

55 Citations (Scopus)

Résumé

We present the Saccharomyces cerevisiae PeptideAtlas composed from 47 diverse experiments and 4.9 million tandem mass spectra. The observed peptides align to 61% of Saccharomyces Genome Database (SGD) open reading frames (ORFs), 49% of the uncharacterized SGD ORFs, 54% of S. cerevisiae ORFs with a Gene Ontology annotation of 'molecular function unknown', and 76% of ORFs with Gene names. We highlight the use of this resource for data mining, construction of high quality lists for targeted proteomics, validation of proteins, and software development.

langue originale	Anglais
Numéro d'article	R106
journal	Genome biology
Volume	7
Numéro de publication	11
Les DOIs	https://doi.org/10.1186/gb-2006-7-11-r106
état	Publié - 13 nov. 2006
Modification externe	Oui

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10.1186/gb-2006-7-11-r106

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title = "Analysis of the Saccharomyces cerevisiae proteome with PeptideAtlas",

abstract = "We present the Saccharomyces cerevisiae PeptideAtlas composed from 47 diverse experiments and 4.9 million tandem mass spectra. The observed peptides align to 61% of Saccharomyces Genome Database (SGD) open reading frames (ORFs), 49% of the uncharacterized SGD ORFs, 54% of S. cerevisiae ORFs with a Gene Ontology annotation of 'molecular function unknown', and 76% of ORFs with Gene names. We highlight the use of this resource for data mining, construction of high quality lists for targeted proteomics, validation of proteins, and software development.",

author = "King, {Nichole L.} and Deutsch, {Eric W.} and Ranish, {Jeffrey A.} and Nesvizhskii, {Alexey I.} and Eddes, {James S.} and Parag Mallick and Jimmy Eng and Frank Desiere and Mark Flory and Martin, {Daniel B.} and Bong Kim and Hookeun Lee and Brian Raught and Ruedi Aebersold",

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AU - King, Nichole L.

AU - Deutsch, Eric W.

AU - Ranish, Jeffrey A.

AU - Nesvizhskii, Alexey I.

AU - Eddes, James S.

AU - Mallick, Parag

AU - Eng, Jimmy

AU - Desiere, Frank

AU - Flory, Mark

AU - Martin, Daniel B.

AU - Kim, Bong

AU - Lee, Hookeun

AU - Raught, Brian

AU - Aebersold, Ruedi

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