Apport et méthodologies innovantes des essais de phase I en oncologie thoracique: des phases 1 aux essais BASKET/plateforme

Oncology has become in the last decade an exciting therapeutic area bridging new scientific concepts and major clinical breakthroughs for the patients and their families. A new era of cancer care and treatments was opened with innovation and multidisciplinary collaborations to achieve higher rates of treatment efficacy based on streamlined molecular analyses and predictive tools generated from precision medicine programs, as well as innovative imaging methods. Facilitating patients’ inclusion in phase I/II studies at an earlier stage of the disease is to acknowledge the early clinical trial as a true therapeutic opportunity within an integrated cancer care management structure.