Autophagy-dependent danger signaling and adaptive immunity to poorly immunogenic tumors

Guido Kroemer, Lorenzo Galluzzi

    Résultats de recherche: Contribution à un journalArticleRevue par des pairs

    12 Citations (Scopus)

    Résumé

    Recent data suggest that autophagy does not influence spontaneous and therapy-elicited tumor infiltration by immune cells in murine models of melanoma and breast carcinoma. These findings, which have been obtained in the absence of a therapeutically relevant anticancer immune response, indicate that the intrinsically low immunogenicity of some tumors cannot be compensated for by increased danger signaling.

    langue originaleAnglais
    Pages (de - à)5686-5691
    Nombre de pages6
    journalOncotarget
    Volume8
    Numéro de publication4
    Les DOIs
    étatPublié - 1 janv. 2017

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