Résumé
Crohn's disease is a chronic inflammatory bowel disorder that has been associated with polymorphisms in the genes encoding the pattern-recognition receptor NOD2 and the autophagic regulator ATG16L1. A new study demonstrates that NOD2 recruits ATG16L1 at bacterial entry sites, thereby bridging innate immunity and autophagy.
langue originale | Anglais |
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Pages (de - à) | R106-R108 |
journal | Current Biology |
Volume | 20 |
Numéro de publication | 3 |
Les DOIs | |
état | Publié - 9 févr. 2010 |