Bortezomib Induces Immunogenic Cell Death in Multiple Myeloma

Laurence Zitvogel; Guido Kroemer

doi:10.1158/2643-3230.BCD-21-0059

Bortezomib Induces Immunogenic Cell Death in Multiple Myeloma

Laurence Zitvogel, Guido Kroemer

Résultats de recherche: Contribution à un journal › Article 'review' › Revue par des pairs

15 Citations (Scopus)

Résumé

As a general rule, successful antineoplastic treatments induce an antitumor immune response, even if they were initially designed to target cancer cell–autonomous pathways. In this issue of Blood Cancer Discovery, Gulla and colleagues reveal that the proteasome inhibitor bortezomib induces immunogenic stress and death in multiple myeloma cells, thus explaining its therapeutic efficacy.

langue originale	Anglais
Pages (de - à)	405-407
Nombre de pages	3
journal	Blood Cancer Discovery
Volume	2
Numéro de publication	5
Les DOIs	https://doi.org/10.1158/2643-3230.BCD-21-0059
état	Publié - 1 sept. 2021

Accès au document

10.1158/2643-3230.BCD-21-0059

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Contient cette citation

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title = "Bortezomib Induces Immunogenic Cell Death in Multiple Myeloma",

abstract = "As a general rule, successful antineoplastic treatments induce an antitumor immune response, even if they were initially designed to target cancer cell–autonomous pathways. In this issue of Blood Cancer Discovery, Gulla and colleagues reveal that the proteasome inhibitor bortezomib induces immunogenic stress and death in multiple myeloma cells, thus explaining its therapeutic efficacy.",

author = "Laurence Zitvogel and Guido Kroemer",

note = "Publisher Copyright: {\textcopyright}2021 American Association for Cancer Research.",

year = "2021",

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doi = "10.1158/2643-3230.BCD-21-0059",

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AU - Zitvogel, Laurence

AU - Kroemer, Guido

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N2 - As a general rule, successful antineoplastic treatments induce an antitumor immune response, even if they were initially designed to target cancer cell–autonomous pathways. In this issue of Blood Cancer Discovery, Gulla and colleagues reveal that the proteasome inhibitor bortezomib induces immunogenic stress and death in multiple myeloma cells, thus explaining its therapeutic efficacy.

AB - As a general rule, successful antineoplastic treatments induce an antitumor immune response, even if they were initially designed to target cancer cell–autonomous pathways. In this issue of Blood Cancer Discovery, Gulla and colleagues reveal that the proteasome inhibitor bortezomib induces immunogenic stress and death in multiple myeloma cells, thus explaining its therapeutic efficacy.

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DO - 10.1158/2643-3230.BCD-21-0059

M3 - Review article

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AN - SCOPUS:85138855007

SN - 2643-3230

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SP - 405

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JO - Blood Cancer Discovery

JF - Blood Cancer Discovery

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