CALM-AF10 fusion gene in leukemias: Simple and inversion-associated translocation (10;11)

Florence Salmon-Nguyen, Maryvonne Busson, Marie Thérèse Daniel, Thierry Leblanc, Olivier A. Bernard, Roland Berger

    Résultats de recherche: Contribution à un journalArticleRevue par des pairs

    11 Citations (Scopus)

    Résumé

    A translocation (10;11)(p12;q14) was observed in two children, one with acute eosinophilic leukemia and the other with acute T-cell lymphoblastic leukemia. The presence of CALM-AF10 fusion was ascertained by reverse transcriptase-polymerase chain reaction (RT-PCR) analysis. Fluorescence in situ hybridization (FISH) analysis showed that AF10 gene splitting was associated with partial inversion of chromosome 11 in the first patient. In addition, FISH analysis also determined the orientation of the CALM gene, 5' telomere to 3' centromere on 11q. (C) 2000 Elsevier Science Inc.

    langue originaleAnglais
    Pages (de - à)137-140
    Nombre de pages4
    journalCancer Genetics and Cytogenetics
    Volume122
    Numéro de publication2
    Les DOIs
    étatPublié - 15 oct. 2000

    Contient cette citation