Résumé
Endoplasmic reticulum stress can stimulate calreticulin (CALR) presentation on the cell surface, promoting the phagocytic uptake of stressed cells by myeloid cells. Recent findings from Wattrus et al. demonstrate that zebrafish and mouse embryonic macrophages engulf CALR-exposing nascent hematopoietic stem cells to ensure the selective survival of stem cells apt for adult hematopoiesis.
langue originale | Anglais |
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Pages (de - à) | 950-952 |
Nombre de pages | 3 |
journal | Trends in Immunology |
Volume | 43 |
Numéro de publication | 12 |
Les DOIs | |
état | Publié - 1 déc. 2022 |