Cancer Cells Thrive on Stress

Lorenzo Galluzzi; Guido Kroemer

doi:10.1016/j.tcb.2019.03.002

Cancer Cells Thrive on Stress

Lorenzo Galluzzi, Guido Kroemer

Résultats de recherche: Contribution à un journal › Brève enquête › Revue par des pairs

10 Citations (Scopus)

Résumé

Glucocorticoids (GCs)are widely used for the management of disease- or therapy-related complications in cancer patients. Recent data indicate that activation of GC receptors (GRs)precipitates breast cancer progression by favoring metastatic dissemination and cell survival at distant sites. These findings call for the re-evaluation of GC usage in patients with cancer.

langue originale	Anglais
Pages (de - à)	449-451
Nombre de pages	3
journal	Trends in Cell Biology
Volume	29
Numéro de publication	6
Les DOIs	https://doi.org/10.1016/j.tcb.2019.03.002
état	Publié - 1 juin 2019

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10.1016/j.tcb.2019.03.002

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title = "Cancer Cells Thrive on Stress",

abstract = "Glucocorticoids (GCs)are widely used for the management of disease- or therapy-related complications in cancer patients. Recent data indicate that activation of GC receptors (GRs)precipitates breast cancer progression by favoring metastatic dissemination and cell survival at distant sites. These findings call for the re-evaluation of GC usage in patients with cancer.",

keywords = "ROR1, circulating tumor cells, dormancy, immunotherapy, social stress, triple negative breast cancer",

author = "Lorenzo Galluzzi and Guido Kroemer",

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AU - Kroemer, Guido

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AB - Glucocorticoids (GCs)are widely used for the management of disease- or therapy-related complications in cancer patients. Recent data indicate that activation of GC receptors (GRs)precipitates breast cancer progression by favoring metastatic dissemination and cell survival at distant sites. These findings call for the re-evaluation of GC usage in patients with cancer.

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KW - circulating tumor cells

KW - dormancy

KW - immunotherapy

KW - social stress

KW - triple negative breast cancer

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JO - Trends in Cell Biology

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