TY - JOUR
T1 - Carbimazole induced eosinophilic granulomatous vasculitis localized to the stomach
AU - Sève, P.
AU - Stankovic, K.
AU - Michalet, V.
AU - Vial, T.
AU - Scoazec, J. Y.
AU - Broussolle, Christiane
PY - 2005/8/1
Y1 - 2005/8/1
N2 - Vasculitis associated with anti-neutrophil cytoplasmic antibodies has been reported in patients treated with anti-thyroid drugs and especially propylthiouracil. We report here a case of granulomatous eosinophilic vasculitis mimicking gastric neoplasm and peripheral eosinophilia in a 27-year-old man who was treated with carbimazole for 5 months for Graves' disease. Clinical and morphologic features resolved within 2 months after stopping the drug, suggesting a causative role for the drug. To our knowledge, this is the first biopsy-proven granulomatous eosinophilic vasculitis associated with this drug.
AB - Vasculitis associated with anti-neutrophil cytoplasmic antibodies has been reported in patients treated with anti-thyroid drugs and especially propylthiouracil. We report here a case of granulomatous eosinophilic vasculitis mimicking gastric neoplasm and peripheral eosinophilia in a 27-year-old man who was treated with carbimazole for 5 months for Graves' disease. Clinical and morphologic features resolved within 2 months after stopping the drug, suggesting a causative role for the drug. To our knowledge, this is the first biopsy-proven granulomatous eosinophilic vasculitis associated with this drug.
KW - Carbimazole
KW - Churg-Strauss syndrome
KW - Eosinophilic granulomatous vasculitis
KW - Stomach
KW - Vasculitis
UR - http://www.scopus.com/inward/record.url?scp=22644445348&partnerID=8YFLogxK
U2 - 10.1111/j.1365-2796.2005.01525.x
DO - 10.1111/j.1365-2796.2005.01525.x
M3 - Article
C2 - 16018796
AN - SCOPUS:22644445348
SN - 0954-6820
VL - 258
SP - 191
EP - 195
JO - Journal of Internal Medicine
JF - Journal of Internal Medicine
IS - 2
ER -