Résumé
Induced pluripotent stem cells were discovered at the end of 2006. They are derived from somatic cells and are functionally close to embryonic stem cells, i.e. characterized by self-renewal and pluripotency properties. They are offering new opportunities in fundamental research and in applied research such as disease modeling, pharmacology research and toxicology. In clinic, they could be used in cell and gene therapies.
Titre traduit de la contribution | Induced pluripotent stem cells: from history to applications |
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langue originale | Français |
Pages (de - à) | 20-32 |
Nombre de pages | 13 |
journal | Hematologie |
Volume | 19 |
Numéro de publication | 1 |
Les DOIs | |
état | Publié - 1 janv. 2013 |
Modification externe | Oui |
mots-clés
- Embryonic stem cells
- Hematopoiesis
- Induced pluripotent stem cells
- Reprogramming