Chimiothérapie locorégionale des métastases hépatiques du cancer colo-rectal.

P. Rougier; P. Lasser; J. P. Droz; D. Elias; M. Ghosn; M. Ducreux; J. Lumbroso; S. Sidibe

Chimiothérapie locorégionale des métastases hépatiques du cancer colo-rectal.

P. Rougier, P. Lasser, J. P. Droz, D. Elias, M. Ghosn, M. Ducreux, J. Lumbroso, S. Sidibe

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Résumé

Locoregional, intra-arterial chemotherapy of liver metastases secondary to colo-rectal cancers is the least damaging among non-surgical treatments. In our experience of 58 cases treated during three years either with intermittent perfusions of 5 FU, or with continuous perfusion of FUDR (by pump), we observed 52% and 53% of objective responses with a survival rate at one year, of 73% and 90% respectively. However, this technique is limited because of locoregional complications and less effective, due to the development of extra-hepatic metastases. The proof of its effectiveness, in terms of survival, is currently being studied in the scope of a prospective and randomized trial with control group.

Titre traduit de la contribution	Locoregional chemotherapy of hepatic metastases of colorectal cancer
langue originale	Français
Pages (de - à)	315-319
Nombre de pages	5
journal	Annales de Gastroenterologie et d'Hepatologie
Volume	23
Numéro de publication	6
état	Publié - 1 janv. 1987

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title = "Chimioth{\'e}rapie locor{\'e}gionale des m{\'e}tastases h{\'e}patiques du cancer colo-rectal.",

abstract = "Locoregional, intra-arterial chemotherapy of liver metastases secondary to colo-rectal cancers is the least damaging among non-surgical treatments. In our experience of 58 cases treated during three years either with intermittent perfusions of 5 FU, or with continuous perfusion of FUDR (by pump), we observed 52% and 53% of objective responses with a survival rate at one year, of 73% and 90% respectively. However, this technique is limited because of locoregional complications and less effective, due to the development of extra-hepatic metastases. The proof of its effectiveness, in terms of survival, is currently being studied in the scope of a prospective and randomized trial with control group.",

author = "P. Rougier and P. Lasser and Droz, {J. P.} and D. Elias and M. Ghosn and M. Ducreux and J. Lumbroso and S. Sidibe",

year = "1987",

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T1 - Chimiothérapie locorégionale des métastases hépatiques du cancer colo-rectal.

AU - Rougier, P.

AU - Lasser, P.

AU - Droz, J. P.

AU - Elias, D.

AU - Ghosn, M.

AU - Ducreux, M.

AU - Lumbroso, J.

AU - Sidibe, S.

PY - 1987/1/1

Y1 - 1987/1/1

N2 - Locoregional, intra-arterial chemotherapy of liver metastases secondary to colo-rectal cancers is the least damaging among non-surgical treatments. In our experience of 58 cases treated during three years either with intermittent perfusions of 5 FU, or with continuous perfusion of FUDR (by pump), we observed 52% and 53% of objective responses with a survival rate at one year, of 73% and 90% respectively. However, this technique is limited because of locoregional complications and less effective, due to the development of extra-hepatic metastases. The proof of its effectiveness, in terms of survival, is currently being studied in the scope of a prospective and randomized trial with control group.

AB - Locoregional, intra-arterial chemotherapy of liver metastases secondary to colo-rectal cancers is the least damaging among non-surgical treatments. In our experience of 58 cases treated during three years either with intermittent perfusions of 5 FU, or with continuous perfusion of FUDR (by pump), we observed 52% and 53% of objective responses with a survival rate at one year, of 73% and 90% respectively. However, this technique is limited because of locoregional complications and less effective, due to the development of extra-hepatic metastases. The proof of its effectiveness, in terms of survival, is currently being studied in the scope of a prospective and randomized trial with control group.

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